Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao +8 more
wiley +1 more source
Interconnected Porous Hydrogels with Tunable Anisotropy Through Aqueous Emulsion Bioprinting
A 3D bioprintable microporous bioink is developed using an aqueous two‐phase system (ATPS) composed of extracellular matrix (ECM) mimetic biopolymers. The ATPS bioink enables the fabrication of interconnected porous architectures with up to 70% porosity, supporting long‐term cell viability and 3D cell alignment, enabling a simultaneous generation of ...
Hugo Edgar‐Vilar +4 more
wiley +1 more source
Plant Metabolic Network 16: expansion of underrepresented plant groups and experimentally supported enzyme data. [PDF]
Hawkins C +5 more
europepmc +1 more source
C5L2 gene polymorphisms and their functional interaction with metabolic-inflammatory networks in T2DM-associated CHD: insights from an integrative genetic and clinical analysis in a Chinese population [PDF]
Mengjia Liu +7 more
openalex +1 more source
Shape‐Morphing Nanoengineered Hydrogel Ribbons as Hemostats
This study introduces a self‐assembling, shape‐morphing nanoengineered hydrogel ribbon system that rapidly forms porous aggregates in situ for efficient hemostasis in trauma and surgical applications. Abstract Rapid and effective hemorrhage control remains a major challenge in trauma and surgical care, particularly for complex or noncompressible wounds.
Ryan Davis Jr +9 more
wiley +1 more source
Analyzing sorbitol biosynthesis using a metabolic network flux model of a lichenized strain of the green microalga Diplosphaera chodatii. [PDF]
Nazem-Bokaee H +3 more
europepmc +1 more source
A new class of living liquid metal composites is introduced, embedding Bacillus subtilis endospores into eutectic gallium–indium (EGaIn). The spores enhance droplet coalescence, strengthen interfacial conductivity, and provide on‐demand electrogenic functionality after germination. The composites exhibit high conductivity, self‐healing, patternability,
Maryam Rezaie, Yang Gao, Seokheun Choi
wiley +1 more source
A modular biosynthetic PVA–gelatin hydrogel crosslinked via visible‐light thiol‐ene chemistry is engineered as a coating for neural electrodes. Optimizing matrix composition and mechanical properties enables the hydrogel to support astrocytic populations that guide neural differentiation and functional maturation.
Martina Genta +4 more
wiley +1 more source
Machine learning methods for predicting essential metabolic genes from Plasmodium falciparum genome-scale metabolic network. [PDF]
Isewon I +4 more
europepmc +1 more source

