Results 301 to 310 of about 898,161 (347)

Growth Signaling Networks Orchestrate Cancer Metabolic Networks

Cold Spring Harbor Perspectives in Medicine
Normal cells grow and divide only when instructed to by signaling pathways stimulated by exogenous growth factors. A nearly ubiquitous feature of cancer cells is their capacity to grow independent of such signals, in an uncontrolled, cell-intrinsic manner.
Brendan D, Manning, Christian C, Dibble
openaire   +2 more sources

Metabolic Networks and Their Evolution

2012
Since the last decade of the twentieth century, systems biology has gained the ability to study the structure and function of genome-scale metabolic networks. These are systems of hundreds to thousands of chemical reactions that sustain life. Most of these reactions are catalyzed by enzymes which are encoded by genes.
openaire   +3 more sources

Network Analysis of Metabolic Networks

2013
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openaire   +1 more source

BUILDING METABOLIC NETWORKS

Materials of the All-Russian Scientific and Practical Conference «CHALLENGING ISSUES IN SYSTEMS MODELING AND PROCESSES»
The article presents a description of the construction and implementation of a program that builds a graph (metabolic network) based on a given stoichiometric matrix. Metabolic networks play a key role in understanding cellular processes and developing new approaches in medical and biotechnological research.
D. Scherbakova, Nadezhda Yudina
openaire   +1 more source

Metabolic Network Analysis

1999
Metabolic network analysis is a tool for investigating the features that identify the topology of a metabolic network and the relative activities of its individual branches. The pillars of metabolic network analysis are mathematical modeling, allowing for a quantitative analysis, biochemical knowledge of, for example, reaction stoichiometry, and the ...
Bjarke Christensen, Jens Nielsen
openaire   +1 more source

Bile acids and the gut microbiota: metabolic interactions and impacts on disease

Nature Reviews Microbiology, 2022
Stephanie Collins, Andrew D Patterson
exaly  

Metabolic Networks

2023
openaire   +1 more source

At a crossroads: how to translate the roles of PI3K in oncogenic and metabolic signalling into improvements in cancer therapy

Nature Reviews Clinical Oncology, 2022
Neil Vasan, Lewis C Cantley
exaly  

Metabolic Network

2020
Shangbin Chen, Alexey Zaikin
openaire   +1 more source

Gut microbiota in human metabolic health and disease

Nature Reviews Microbiology, 2020
Yong Fan, Oluf Borbye Pedersen
exaly