Results 321 to 330 of about 4,047,137 (345)
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On representation of metabolic pathways
Biosystems, 1998Problems involved in representation of metabolism are dealt with. The specific characteristics of the various ways (verbal, graphical and by electronic means), their advantages and limitations are discussed. New developments in research pose challenges for adequate and clear demonstration of results. Comments on nomenclature and on style are included.
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Rapid and Efficient One-Step Metabolic Pathway Integration in E. coli.
ACS Synthetic Biology, 2016Methods for importing heterologous genes into genetically tractable hosts are among the most desired tools of synthetic biology. Easy plug-and-play construction methods to rapidly test genes and pathways stably in the host genome would expedite synthetic
Marcelo C. Bassalo +7 more
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Combinatorial chemistry & high throughput screening, 2016
A metabolic pathway is a series of biological processes providing necessary molecules and energies for an organism, which could be essential to the lives of the living organisms.
Lei Chen, C. Chu, Kaiyan Feng
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A metabolic pathway is a series of biological processes providing necessary molecules and energies for an organism, which could be essential to the lives of the living organisms.
Lei Chen, C. Chu, Kaiyan Feng
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Metabolic Pathways in the Apicoplast of Apicomplexa
2010Intracellular parasites of the phylum Apicomplexa harbor a plastid-like organelle called apicoplast that is the most reduced organelle of this type known. Due to the medical importance of some members of Apicomplexa, a number of fully sequenced genomes are available that have allowed to assemble metabolic pathways also from the apicoplast and have ...
Seeber, Frank, Soldati-Favre, Dominique
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1986
The routes by which drugs may be metabolised or biotransformed are many and varied and include the chemical reactions of oxidation, reduction, hydrolysis, hydration, conjugation and condensation. It is important that these pathways are studied as the route of metabolism of a drug can determine whether it shows any pharmacological or toxicological ...
Paul Skett, G. Gordon Gibson
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The routes by which drugs may be metabolised or biotransformed are many and varied and include the chemical reactions of oxidation, reduction, hydrolysis, hydration, conjugation and condensation. It is important that these pathways are studied as the route of metabolism of a drug can determine whether it shows any pharmacological or toxicological ...
Paul Skett, G. Gordon Gibson
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The NGF Metabolic Pathway in the CNS and its Dysregulation in Down Syndrome and Alzheimer's Disease.
Current Alzheimer Research, 2015It is well established that individuals with Down syndrome develop Alzheimer's disease neuropathology by middle age. Both in Alzheimer's disease and Down syndrome, this is accompanied by the atrophy of NGF-dependent cholinergic neurons of the basal ...
M. F. Iulita, A. Cuello
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Metabolic pathways regulated by p63
Biochemical and Biophysical Research Communications, 2017The transcription factor p63 belongs to the p53-family and is a master regulator of proliferative potential, lineage specification, and differentiation in epithelia during development and tissue homeostasis. In cancer, p63 contribution is isoform-specific, with both oncogenic and tumour suppressive roles attributed, for ΔNp63 and TAp63, respectively ...
Gerry Melino +11 more
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Salvage pathways in glycosphingolipid metabolism
Biochimie, 2003In this review, the focus is on the role of salvage pathways in glycosphingolipid, particularly, ganglioside metabolism. Ganglioside de novo biosynthesis, that begins with the formation of ceramide and continues with the sequential glycosylation steps producing the oligosaccharide moieties, is briefly outlined in its enzymological and cell-topological ...
G. Tettamanti +3 more
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Identifying Branched Metabolic Pathways by Merging Linear Metabolic Pathways
2011This paper presents a graph-based algorithm for identifying complex metabolic pathways in multi-genome scale metabolic data. These complex pathways are called branched pathways because they can arrive at a target compound through combinations of pathways that split compounds into smaller ones, work in parallel with many compounds, and join compounds ...
George N. Bennett +2 more
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ALTERNATIVE METABOLIC PATHWAYS
Physiological Reviews, 1950Van R. Potter, Charles Heidelberger
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