Results 181 to 190 of about 59,794 (290)

The emerging role of CAMK1D in diabetes, metabolism and feeding behaviours: A mechanistic systematic review

open access: yesClinical and Translational Discovery, Volume 6, Issue 1, February 2026.
This systematic review synthesizes evidence from published studies, GWAS and grey literature (patents) to show that CAMK1D is implicated in diabetes, obesity, insulin resistance and altered feeding behaviours, with diagnostic potential and mechanistic relevance through regulatory binding and tissue‐specific effects.
Livio Tarchi   +13 more
wiley   +1 more source

Panax notoginseng Saponins Ameliorate High‐Fat Diet‐Induced Liver Injury via Mechanisms Involving TLR4‐Mediated Signaling and Lipid Metabolism

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
Panax notoginseng saponins (PNS) ameliorate high‐fat diet‐induced liver injury by modulating the LPS‐TLR4/MyD88 axis. This leads to the concurrent suppression of NF‐κB and MAPK signaling, which reduces oxidative stress and inflammation while improving lipid metabolism.
Rong Li   +11 more
wiley   +1 more source

Identification of a Novel Missense Homozygous Variant in LINS1 in Two Distinct Iranian Families With Consanguineous Marriage

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 2, February 2026.
A novel homozygous missense variant in LINS1 (c.1354G>C; p.Ala452Pro) was identified in two consanguineous families with autosomal recessive intellectual disability, supporting the gene's role in neurodevelopment and its relevance in genetic diagnosis and counseling of ARID. Reported pathogenic LINS1 variants.
Elham Alimoradi   +8 more
wiley   +1 more source

Soil extracellular enzymes drive soil carbon accumulation under elevated CO2

open access: yesFunctional Ecology, Volume 40, Issue 2, Page 347-359, February 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Human‐driven increases in atmospheric CO2 (eCO2) are stimulating plant growth, thereby increasing the input of plant‐derived carbon into soils. The fate of this additional carbon depends on the capacity of soil microbiomes to decompose and transform organic matter, a ...
Yixuan Zhang   +21 more
wiley   +1 more source

Comparative multi‐omics in female mice reveals tissue‐specific vulnerabilities to chronic alcohol intake

open access: yesAlcohol, Clinical and Experimental Research, Volume 50, Issue 2, February 2026.
Using mice, we applied multi‐omics to compare liver and skeletal muscle after chronic alcohol consumption. The liver responded more strongly across genes, proteins, and metabolites, with a lowered PC:PE ratio. Muscle showed inflammation, extracellular matrix activation, impaired mitochondrial energetics, and an elevated PC:PE ratio. Lipidomics affected
Craig R. G. Willis   +6 more
wiley   +1 more source

Time-course changes in energy expenditure in sepsis: a prospective observational study. [PDF]

open access: yesAnn Intensive Care
Wasyluk W   +6 more
europepmc   +1 more source

The aporetic dialogs of Modena on gender differences: Is it all about testosterone? Episode III: Mathematics

open access: yesAndrology, Volume 14, Issue 2, Page 335-344, February 2026.
Abstract This report is the transcript of what was discussed in a convention at the Endocrinology Unit in Modena, Italy, in the form of the aporetic dialogs of ancient Greece. It is the third episode of a series of four discussions on the differences between males and females, with a multidisciplinary approach. In this work, the role of testosterone in
Giulia Brigante   +6 more
wiley   +1 more source

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