Results 181 to 190 of about 59,794 (290)
This systematic review synthesizes evidence from published studies, GWAS and grey literature (patents) to show that CAMK1D is implicated in diabetes, obesity, insulin resistance and altered feeding behaviours, with diagnostic potential and mechanistic relevance through regulatory binding and tissue‐specific effects.
Livio Tarchi +13 more
wiley +1 more source
Panax notoginseng saponins (PNS) ameliorate high‐fat diet‐induced liver injury by modulating the LPS‐TLR4/MyD88 axis. This leads to the concurrent suppression of NF‐κB and MAPK signaling, which reduces oxidative stress and inflammation while improving lipid metabolism.
Rong Li +11 more
wiley +1 more source
Infantile Epsilon-Sarcoglycan (SGCE) Myoclonus-Dystonia: Diagnostic Pitfalls and Poor Response to Pharmacologic Treatment. [PDF]
Pissarra R, Dias L, Sousa R, Melo C.
europepmc +1 more source
A novel homozygous missense variant in LINS1 (c.1354G>C; p.Ala452Pro) was identified in two consanguineous families with autosomal recessive intellectual disability, supporting the gene's role in neurodevelopment and its relevance in genetic diagnosis and counseling of ARID. Reported pathogenic LINS1 variants.
Elham Alimoradi +8 more
wiley +1 more source
Diabetes and the Developing Mind: Intelligence Quotient (IQ) and Its Associations in Indian Children and Youth With Type 1 Diabetes. [PDF]
Wagle-Patki SS +6 more
europepmc +1 more source
Soil extracellular enzymes drive soil carbon accumulation under elevated CO2
Read the free Plain Language Summary for this article on the Journal blog. Abstract Human‐driven increases in atmospheric CO2 (eCO2) are stimulating plant growth, thereby increasing the input of plant‐derived carbon into soils. The fate of this additional carbon depends on the capacity of soil microbiomes to decompose and transform organic matter, a ...
Yixuan Zhang +21 more
wiley +1 more source
Using mice, we applied multi‐omics to compare liver and skeletal muscle after chronic alcohol consumption. The liver responded more strongly across genes, proteins, and metabolites, with a lowered PC:PE ratio. Muscle showed inflammation, extracellular matrix activation, impaired mitochondrial energetics, and an elevated PC:PE ratio. Lipidomics affected
Craig R. G. Willis +6 more
wiley +1 more source
Time-course changes in energy expenditure in sepsis: a prospective observational study. [PDF]
Wasyluk W +6 more
europepmc +1 more source
Abstract This report is the transcript of what was discussed in a convention at the Endocrinology Unit in Modena, Italy, in the form of the aporetic dialogs of ancient Greece. It is the third episode of a series of four discussions on the differences between males and females, with a multidisciplinary approach. In this work, the role of testosterone in
Giulia Brigante +6 more
wiley +1 more source

