Abstract Circulating cell‐free DNA (cfDNA), circulating tumour DNA (ctDNA) and inflammatory cytokines have prognostic and predictive value in oncology. However, the effects of acute exercise on cfDNA levels are unknown. Here, we explore the kinetics of cfDNA, ctDNA and cytokines upon an incremental exercise test in a pilot cohort of cancer patients ...
Elmo W. I. Neuberger +10 more
wiley +1 more source
High-Resolution Magic Angle Spinning Metabolomic Profiling of IDH-Wild-Type Glioblastoma Reveals a Composite Surgical Sampling Signature Shaped by Clinical and Anatomical Tumor Features. [PDF]
Todeschi J +4 more
europepmc +1 more source
Abstract figure legend Vibrodissociated Pukinje neurons retain active synaptic connections, including those from adhering fragments of the climbing fibre. These fragments generate excitatory synaptic events and the frequency of these events is increased by exposure to either NMDA [with d‐serine (d‐ser) as a co‐agonist] or glycine at a high (100 µM ...
David C. H. Benton +7 more
wiley +1 more source
The Mitochondrial NAD Transporter SLC25A51 in Adipocytes Regulates Adipose Tissue Mitochondrial Function and Systemic Metabolism During Aging. [PDF]
Kojima D +19 more
europepmc +1 more source
Abstract figure legend This study examined whether supine cycling exercise, with or without artificial gravity, preserves resting metabolic rate (RMR) during 60 days of head‐down tilt bed rest, and whether RMR responses align with integrated multivariate physiological adaptations.
Saul Martin‐Rodriguez +6 more
wiley +1 more source
Efficacy of GLP-1 analog peptides, semaglutide, tirzepatide, and retatrutide on MC4R deficient obesity and their comparison. [PDF]
Hitaka K +3 more
europepmc +1 more source
Effect of Using the Food Quotient as a Proxy of the Respiratory Quotient in the Calculation of Energy Expenditure by the Doubly Labeled Water Method in Older Adults. [PDF]
de Mello DGA +4 more
europepmc +1 more source
A STUDY OF PURINE METABOLISM IN PRIMATES BASED ON ALLANTOIN AND URIC ACID QUOTIENTS IN PLASMA
OHTAWA, Takeyuki +9 more
openaire +1 more source
Statement on the findings presented in the Toxicological Profile for Mercury issued by the US ATSDR
Abstract The European Food Safety Authority (EFSA) was requested by the European Commission to deliver a statement on the findings presented in the Toxicological Profile for Mercury issued by the US Agency for Toxic Substances and Disease Registry (ATSDR) in 2024. The statement was endorsed by the CONTAM Panel before approval by EFSA. Although some key
European Food Safety Authority (EFSA) +7 more
wiley +1 more source

