Results 181 to 190 of about 36,391 (234)
Abstract Type 1 diabetes (T1D) is a chronic autoimmune disease that results in loss of insulin‐secreting pancreatic β‐cells in the islets of Langerhans. A diagnosis of T1D is typically associated with children and adolescents, yet half of all diagnoses of T1D are made in adults.
Sufyan Hussain +16 more
wiley +1 more source
Background Although attention‐deficit/hyperactivity disorder (ADHD) with familial risk for bipolar I disorder (BD) may represent a more severe illness conferring greater risk for developing BD, associated neurostructural substrates remain poorly understood.
Biqiu Tang +5 more
wiley +1 more source
Urine‐Derived iPSC Neurospheres Uncover Proteomic Correlates of Clinical Severity in Dravet Syndrome
Urine epithelial cells from Dravet syndrome (DS) patients carrying distinct SCN1A variants were reprogrammed into induced pluripotent stem cells (iPSCs) and differentiated into neural stem cells (NSCs) to generate patient‐derived neurospheres. Three neurosphere lines were analyzed in biological triplicates using isobaric quantitative proteomics ...
Michele Martins +9 more
wiley +1 more source
ABSTRACT Endurance performance determinants are typically assessed under fresh conditions, although physiological and mechanical characteristics deteriorate during prolonged exercise, a phenomenon recently termed durability or resilience. However, it is unclear whether durability and mechanisms underpinning it differ between sexes.
Diego Jaén‐Carrillo +3 more
wiley +1 more source
Decomposition of leaf litter of Phillyrea angustifolia L. and mixed aboveground litter of herbaceous species from a mediterranean maquis. [PDF]
DE MARCO, ANNA +3 more
core
THE METABOLIC RATE AND RESPIRATORY QUOTIENTS OF RATS ON A FAT-DEFICIENT DIET
Laurence G. Wesson, George O. Burr
openaire +1 more source
Estimated exercise‐induced maximal myocardial blood flow in untrained and endurance‐trained men
Abstract The heart critically depends on a continuous supply of oxygen, provided by myocardial blood flow (MBF), but reliable quantification of MBF during maximal exercise is not feasible in humans. We measured MBF at rest and during similar absolute (150 W) and relative (70% of V̇O2max${{\dot{V}}_{{{{\mathrm{O}}}_{\mathrm{2}}}{\mathrm{max ...
Ilkka Heinonen +3 more
wiley +1 more source
The 2024 European Union report on pesticide residues in food
Abstract Under European Union legislation (Article 32, Regulation (EC) No 396/2005), the European Food Safety Authority publishes an annual report assessing pesticide residue levels in food. In 2024, 9842 samples were analysed as part of the EU‐coordinated multiannual control programme subset, of which 1.2% were found to be non‐compliant.
European Food Safety Authority (EFSA) +4 more
wiley +1 more source
Changes of carbohydrate metabolism in disorders of thyroid function [PDF]
Bottermann, P. +4 more
core
Flavonoid Oxime Carbamate Derivatives: Reversal of Multidrug Resistance in Cancer Cells
A set of 23 new flavonoid oxime carbamates was synthesized and evaluated as multidrug resistance (MDR) reversers in ABCB1‐transfected mouse lymphoma cells. All derivatives strongly inhibited P‐glycoprotein (P‐gp) efflux activity in a transport assay, while most selected compounds behaved as ATPase inhibitors. In drug combination assays, they interacted
Filipa Barbosa +5 more
wiley +1 more source

