Results 181 to 190 of about 36,391 (234)

An international consensus on screening and monitoring early‐stage type 1 diabetes: A roadmap to European implementation

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3535-3556, May 2026.
Abstract Type 1 diabetes (T1D) is a chronic autoimmune disease that results in loss of insulin‐secreting pancreatic β‐cells in the islets of Langerhans. A diagnosis of T1D is typically associated with children and adolescents, yet half of all diagnoses of T1D are made in adults.
Sufyan Hussain   +16 more
wiley   +1 more source

Regional cerebellar structural deficits distinguish psychostimulant‐free ADHD youth with and without familial risk for bipolar I disorder: a cross‐sectional morphometric analysis

open access: yesJournal of Child Psychology and Psychiatry, Volume 67, Issue 5, Page 766-776, May 2026.
Background Although attention‐deficit/hyperactivity disorder (ADHD) with familial risk for bipolar I disorder (BD) may represent a more severe illness conferring greater risk for developing BD, associated neurostructural substrates remain poorly understood.
Biqiu Tang   +5 more
wiley   +1 more source

Urine‐Derived iPSC Neurospheres Uncover Proteomic Correlates of Clinical Severity in Dravet Syndrome

open access: yesJournal of Neurochemistry, Volume 170, Issue 5, May 2026.
Urine epithelial cells from Dravet syndrome (DS) patients carrying distinct SCN1A variants were reprogrammed into induced pluripotent stem cells (iPSCs) and differentiated into neural stem cells (NSCs) to generate patient‐derived neurospheres. Three neurosphere lines were analyzed in biological triplicates using isobaric quantitative proteomics ...
Michele Martins   +9 more
wiley   +1 more source

Highly Trained Female Runners Show Greater Durability and Physiological Resilience Than Performance‐Matched Male Counterparts

open access: yesScandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 5, May 2026.
ABSTRACT Endurance performance determinants are typically assessed under fresh conditions, although physiological and mechanical characteristics deteriorate during prolonged exercise, a phenomenon recently termed durability or resilience. However, it is unclear whether durability and mechanisms underpinning it differ between sexes.
Diego Jaén‐Carrillo   +3 more
wiley   +1 more source

THE METABOLIC RATE AND RESPIRATORY QUOTIENTS OF RATS ON A FAT-DEFICIENT DIET

open access: yesJournal of Biological Chemistry, 1931
Laurence G. Wesson, George O. Burr
openaire   +1 more source

Estimated exercise‐induced maximal myocardial blood flow in untrained and endurance‐trained men

open access: yesExperimental Physiology, Volume 111, Issue 5, Page 2543-2552, 1 May 2026.
Abstract The heart critically depends on a continuous supply of oxygen, provided by myocardial blood flow (MBF), but reliable quantification of MBF during maximal exercise is not feasible in humans. We measured MBF at rest and during similar absolute (150 W) and relative (70% of V̇O2max${{\dot{V}}_{{{{\mathrm{O}}}_{\mathrm{2}}}{\mathrm{max ...
Ilkka Heinonen   +3 more
wiley   +1 more source

The 2024 European Union report on pesticide residues in food

open access: yesEFSA Journal, Volume 24, Issue 5, May 2026.
Abstract Under European Union legislation (Article 32, Regulation (EC) No 396/2005), the European Food Safety Authority publishes an annual report assessing pesticide residue levels in food. In 2024, 9842 samples were analysed as part of the EU‐coordinated multiannual control programme subset, of which 1.2% were found to be non‐compliant.
European Food Safety Authority (EFSA)   +4 more
wiley   +1 more source

Changes of carbohydrate metabolism in disorders of thyroid function [PDF]

open access: yes, 1970
Bottermann, P.   +4 more
core  

Flavonoid Oxime Carbamate Derivatives: Reversal of Multidrug Resistance in Cancer Cells

open access: yesChemMedChem, Volume 21, Issue 7, 14 April 2026.
A set of 23 new flavonoid oxime carbamates was synthesized and evaluated as multidrug resistance (MDR) reversers in ABCB1‐transfected mouse lymphoma cells. All derivatives strongly inhibited P‐glycoprotein (P‐gp) efflux activity in a transport assay, while most selected compounds behaved as ATPase inhibitors. In drug combination assays, they interacted
Filipa Barbosa   +5 more
wiley   +1 more source

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