Results 51 to 60 of about 23,382 (239)

Infusion rate adjustment in enzyme replacement therapy with pabinafusp alfa for mucopolysaccharidosis II

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Enzyme replacement therapy (ERT) for mucopolysaccharidosis II (MPS II) requires long‐term, weekly intravenous infusions often lasting over 3 h each time, which can burden paediatric patients and caregivers and negatively affect their quality of life and treatment compliance.
Kimitoshi Nakamura, Norio Sakai, Hideaki Hirai, Naoko Takasao, Ryo Ibaraki, Tatsuyoshi Yamamoto, Yuji Sato   +6 more
wiley   +1 more source

Short-Term Impacts on Soil Biological Properties After Amendment with Biochar from Residual Forestry Biomass

Agriculture
The increasing challenges posed by climate change demand efficient strategies to mitigate soil degradation. Valorization of low-grade residual forestry biomass (acacia) into biochar could be used as a soil amendment strategy.
Ana Carolina Morim, Márcia Santos, Luís A. C. Tarelho, Flávio C. Silva   +3 more
doaj   +1 more source

Biochar alters the soil microbiological activity of sugarcane fields over time [PDF]

Scientia Agricola
There are few long-term field studies on the effects of biochar on soil microbial abundance and diversity. This study aimed to evaluate doses of biochar in combination with mineral fertilizer on the activity and diversity of microorganisms in the soil of
Erika Manuela Gonçalves Lopes, Mauro Franco Castro Mota, José Mendes dos Santos Júnior, Matheus Mendes Reis, Leidivan Almeida Frazão, Luiz Arnaldo Fernandes   +5 more
doaj   +1 more source

Effect of Vitamin Deficiencies on Basal Metabolism and Respiratory Quotient in Rats.

Experimental Biology and Medicine, 1942
SummaryRiboflavin and pantothenic acid deficiencies in rats do not alter the BMR. A definite decrease in the BMR was observed in severe vitamin B6 deficiency. All rats showing a riboflavin, vitamin B6, and pantothenic acid deficiency had a higher RQ than normal rats. The possible explanation for this increased RQ is given.
D. Orsini, H. A. Waisman, C. A. Elvehjem
openaire   +1 more source

Expanding Metabolic Online Monitoring Capabilities in 96‐Deepwell Microtiter Plates by Combining Optoelectronic O2 and CO2 Sensors

Biotechnology and Bioengineering, EarlyView.
ABSTRACT To increase the information content in early stages of bioprocess development, various technologies have been introduced for monitoring cultivations in microtiter plates (MTPs). Besides spectroscopical measurements, like in the BioLector technology, optical measurements with luminescent sensors, placed directly in the cultivation medium ...
Robert Dinger, David Pfeifer, David Flitsch, Jan P. Fischer, Clemens Lattermann, Sergey M. Borisov, Jochen Büchs   +6 more
wiley   +1 more source

Seminars in epileptology: Holistic management of epilepsy in adults with intellectual development disorders

Epileptic Disorders, EarlyView.
Abstract This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic,
Elena Fonseca, Antonella Riva, Samuel López‐Maza, Malin Zaddach, Marie‐Claire Porter, Ingo Borggraefe, Lance Watkins, Andreas Schulze‐Bonhage, Rohit Shankar, Pasquale Striano, Lina Nashef   +10 more
wiley   +1 more source

Influencia de la aplicación de vinaza en actividad y biomasa microbiana en un Entic Dystropept y un Fluventic haplustoll del Valle del Cauca, Colombia

Acta Agronómica, 2009
<span style="font-size: 10pt; font-family: Verdana; mso-fareast-font-family: 'Times New Roman'; mso-bidi-font-family: 'Times New Roman'; mso-ansi-language: ES; mso-fareast-language: ES; mso-bidi-language: AR-SA;">Con la aplicación de vinaza ...
Bonilla Correa Carmen Rosa, Madriñán Molina Raúl, Montenegro Gómez Sandra Patricia, Menjivar Flórez Juan Carlos   +3 more
doaj  

Add‐on treatment with vinpocetine reduces seizure frequency and improves comorbidities in patients with loss‐of‐function γ‐aminobutyric acid type A receptor variants

Epilepsia, EarlyView.
Abstract Objective The semisynthetic compound vinpocetine has gained attention as a potential precision medicine for developmental and epileptic encephalopathies caused by loss‐of‐function (LoF) variants in γ‐aminobutyric acid type A (GABAA) receptor genes. As a positive allosteric modulator of GABAA receptors, case reports suggest that vinpocetine can
Cathrine E. Gjerulfsen, Vivian W. Y. Liao, Tomasz S. Mieszczanek, Anne V. Jakobsen, Elena Gardella, Kern Olofsson, Marina Nikanorova, Allan Bayat, Sebastian Ortiz, Sarah Weckhuysen, Cecilie Johannessen Landmark, Orrin Devinsky, Mary Chebib, Philip K. Ahring, Guido Rubboli, Rikke S. Møller   +15 more
wiley   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

The effect of deforestation and land use change on ecophysiology indices of soil carbon and nitrogen [PDF]

مجله جنگل ایران, 2015
Carbon dioxide, methane and nitrous oxide are the most important greenhouse gases. The changes of these gases are mainly affected by the variability of carbon and nitrogen ecophysiology indices.
doaj