Results 91 to 100 of about 2,197,729 (354)

Measurements of Penetration and Detoxification of PS II Herbicides in Whole Leaves by a Fluorometric Method [PDF]

, 1984
The effect of herbicides that inhibit the photosynthetic electron transport at the photosystem II acceptor side has been analyzed in whole plants by using a fluorometric method.
Gräber, Peter, Kötter, C., Renger, Gernot, Voss, M.   +3 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Characterization of Listeria monocytogenes strains isolated from soil under organic carrot farming

Frontiers in Microbiology
IntroductionListeria monocytogenes are Gram-positive, non-spore-producing rods that are the etiological agent of listeriosis. L. monocytogenes is isolated from soil, water, sewage, rotting vegetation, and the main source of these rods for humans is food (
Maciej Nowak, Zbigniew Paluszak, Natalia Wiktorczyk-Kapischke, Katarzyna Grudlewska-Buda, Anna Budzyńska, Joanna Skonieczna-Kurpiel, Ewa Wałecka-Zacharska, Monika Huse-Kutowska, Krzysztof Skowron   +8 more
doaj   +1 more source

Relationship between muscle metabolic rate and muscle torque complexity during fatiguing intermittent isometric contractions in humans

Physiological Reports, 2019
To test the hypothesis that a system’s metabolic rate and the complexity of fluctuations in the output of that system are related, thirteen healthy participants performed intermittent isometric knee extensor contractions at intensities where a rise in ...
Jamie Pethick, Samantha L. Winter, Mark Burnley   +2 more
doaj   +1 more source

Branching principles of animal and plant networks identified by combining extensive data, machine learning, and modeling

, 2020
Branching in vascular networks and in overall organismic form is one of the most common and ancient features of multicellular plants, fungi, and animals.
Bentley, Lisa P., Brummer, Alexander B, Buzzard, Vanessa, Enquist, Brian J., Gray, Andrew, Lymperopoulos, Panagiotis, Oliveras, Imma, Savage, Van M., Shen, Jocelyn, Tekin, Elif   +9 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Juvenile-specific high heat production contributes to the initial step of endothermic development in Pacific bluefin tuna

Frontiers in Physiology
Pacific bluefin tuna (Thynnus orientalis; PBT) can maintain their body temperature above ambient water (i.e., thermal excess) through high heat production and heat retention.
Takaaki K. Abe, Takaaki K. Abe, Maho Fuke, Ko Fujioka, Ko Fujioka, Takuji Noda, Hiroyuki Irino, Yoshikazu Kitadani, Hiromu Fukuda, Morten Bo Søndergaard Svendsen, John Fleng Steffensen, Takashi Kitagawa, Takashi Kitagawa   +12 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

The effect of body size and inbreeding on cancer mortality in breeds of the domestic dog: a test of the multi-stage model of carcinogenesis

Royal Society Open Science
Cancer is a leading cause of death in domestic dogs. Deaths due to cancer vary widely among breeds, providing an opportunity for testing the multi-stage model of carcinogenesis.
Leonard Nunney
doaj   +1 more source