Causal Effects of Basal Metabolic Rate on Cardiovascular Disease: A Bidirectional Mendelian Randomization Study [PDF]
Journal of the American Heart AssociationBackground Despite the health effects of basal metabolic rate (BMR), the causal effect of BMR on cardiovascular diseases (CVDs) remains undetermined. To elucidate the causal nature, Mendelian randomization (MR) analyses were performed.
Jinwei Tian, Bo Yu, Xinxin Liu
exaly +4 more sources
Causal effects of basal metabolic rate and adiposity on obstructive sleep apnea: univariable, multivariable, and bidirectional Mendelian randomization evidence. [PDF]
Future Sci OABackground Obstructive sleep apnea (OSA) is a common disorder strongly associated with obesity, yet the causal contribution of basal metabolic rate to OSA and the directionality of the OSA–metabolism relationship remain unclear.
Zhang M +5 more
europepmc +2 more sources
Effect of Basal Metabolic Rate on Cancer: A Mendelian Randomization Study
Frontiers in Genetics, 2021 Background: Basal metabolic rate is associated with cancer, but these observations are open to confounding. Limited evidence from Mendelian randomization studies exists, with inconclusive results. Moreover, whether basal metabolic rate has a similar role
Catherine Mary Schooling, Jack C M Ng
exaly +3 more sources
The association between basal metabolic rate and ischemic stroke: a Mendelian randomization study. [PDF]
Front NeurolObjectiveThis study aims to elucidate the potential impact of basal metabolic rate on ischemic stroke at the genetic prediction level through a two-sample Mendelian randomization analysis.MethodsUsing summary data from genome-wide association studies, we
Chen Y +11 more
europepmc +2 more sources
Effect of Basal Metabolic Rate on Osteoporosis: A Mendelian Randomization Study
Frontiers in Public Health, 2023 PurposeBasal metabolic rate may play a key role in the pathogenesis and progression of osteoporosis. We performed Mendelian random analysis to evaluate the causal relationship between basal metabolic rate and osteoporosis.MethodsInstrumental variables ...
Qianyi Peng, Zhiwen Ye, Shilang Xiong
exaly +3 more sources
Basal metabolic rate shapes the development and progression of hepatocellular carcinoma. [PDF]
BMC CancerBackground Among several cancer risk factors, the variation in basal metabolism rate (BMR), which constitutes up to 70% of total energy expenditures in humans, may be causally linked with neoplasm development.
Maciak S +5 more
europepmc +2 more sources
The impact of physical activity and basal metabolic rate as mediators of years since menopause on sarcopenia in elderly women. [PDF]
Open Med (Wars)This study examined the mediating effects of physical activity (PA) and basal metabolic rate (BMR) on the relationship between years since menopause and sarcopenia in community-dwelling elderly women.
Dong X, Zhou L, Wang L, Liu X, Li S.
europepmc +2 more sources
Sex-specific Mendelian randomization phenome-wide association study of basal metabolic rate. [PDF]
Sci RepObservationally, higher basal metabolic rate (BMR) is associated with metabolism-related disorders, cancer, aging, and mortality. In this Mendelian randomization (MR) phenome-wide association study, using two-sample MR methods, we systematically and ...
Ng JCM, Schooling CM.
europepmc +2 more sources
The association between basal metabolic rate and osteoarthritis: a Mendelian randomization study. [PDF]
BMC Med Genomics, 2023 Background The role of the basal metabolic rate (BMR) in osteoarthritis (OA) remains unclear, as previous retrospective studies have produced inconsistent results. Therefore, we performed a Mendelian randomization (MR) study to systematically investigate
Zhou J +9 more
europepmc +2 more sources
Association between basal metabolic rate and cognitive function in Chinese older adults: the mediating effect of sarcopenia. [PDF]
BMC GeriatrBackground Cognitive aging poses a major worldwide health concern. The association between basal metabolic rate (BMR) and cognition isn’t well understood. This research examines sarcopenia’s potential role as a mediator: linking BMR to cognitive function.
Ding H +5 more
europepmc +2 more sources