The association between basal metabolic rate and ischemic stroke: a Mendelian randomization study [PDF]
ObjectiveThis study aims to elucidate the potential impact of basal metabolic rate on ischemic stroke at the genetic prediction level through a two-sample Mendelian randomization analysis.MethodsUsing summary data from genome-wide association studies, we
Yizhou Chen +19 more
doaj +6 more sources
Effect of Basal Metabolic Rate on Cancer: A Mendelian Randomization Study [PDF]
Background: Basal metabolic rate is associated with cancer, but these observations are open to confounding. Limited evidence from Mendelian randomization studies exists, with inconclusive results. Moreover, whether basal metabolic rate has a similar role
Jack C. M. Ng +2 more
doaj +4 more sources
Effect of basal metabolic rate on osteoporosis: A Mendelian randomization study [PDF]
PurposeBasal metabolic rate may play a key role in the pathogenesis and progression of osteoporosis. We performed Mendelian random analysis to evaluate the causal relationship between basal metabolic rate and osteoporosis.MethodsInstrumental variables ...
Jingyu Zhou +15 more
doaj +4 more sources
Causal Effects of Basal Metabolic Rate on Cardiovascular Disease: A Bidirectional Mendelian Randomization Study [PDF]
Background Despite the health effects of basal metabolic rate (BMR), the causal effect of BMR on cardiovascular diseases (CVDs) remains undetermined. To elucidate the causal nature, Mendelian randomization (MR) analyses were performed.
Peng Zhao +6 more
doaj +4 more sources
Basal metabolic rate shapes the development and progression of hepatocellular carcinoma [PDF]
Background Among several cancer risk factors, the variation in basal metabolism rate (BMR), which constitutes up to 70% of total energy expenditures in humans, may be causally linked with neoplasm development.
Sebastian Maciak +5 more
doaj +2 more sources
The impact of physical activity and basal metabolic rate as mediators of years since menopause on sarcopenia in elderly women [PDF]
This study examined the mediating effects of physical activity (PA) and basal metabolic rate (BMR) on the relationship between years since menopause and sarcopenia in community-dwelling elderly women.
Dong Xinying +4 more
doaj +2 more sources
Sex-specific Mendelian randomization phenome-wide association study of basal metabolic rate [PDF]
Observationally, higher basal metabolic rate (BMR) is associated with metabolism-related disorders, cancer, aging, and mortality. In this Mendelian randomization (MR) phenome-wide association study, using two-sample MR methods, we systematically and ...
Jack C. M. Ng, C. Mary Schooling
doaj +2 more sources
The association between basal metabolic rate and osteoarthritis: a Mendelian randomization study [PDF]
Background The role of the basal metabolic rate (BMR) in osteoarthritis (OA) remains unclear, as previous retrospective studies have produced inconsistent results. Therefore, we performed a Mendelian randomization (MR) study to systematically investigate
Jingyu Zhou +9 more
doaj +2 more sources
Effect of basal metabolic rate on lifespan: a sex-specific Mendelian randomization study [PDF]
Observationally, the association of basal metabolic rate (BMR) with mortality is mixed, although some ageing theories suggest that higher BMR should reduce lifespan. It remains unclear whether a causal association exists.
Jack C. M. Ng, C. Mary Schooling
doaj +2 more sources
Association between basal metabolic rate and cognitive function in Chinese older adults: the mediating effect of sarcopenia [PDF]
Background Cognitive aging poses a major worldwide health concern. The association between basal metabolic rate (BMR) and cognition isn’t well understood. This research examines sarcopenia’s potential role as a mediator: linking BMR to cognitive function.
Hong Ding +5 more
doaj +2 more sources

