Results 211 to 220 of about 2,197,729 (354)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Associations between metabolic rate and personality in a free-living small mammal are driven by date of birth. [PDF]

R Soc Open Sci
Qiu J, Schradin C, Mata A, Pillay N, Rödel H.   +4 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Basal metabolic rate predicts dementia in community-dwelling older adults: a 5-year longitudinal study. [PDF]

Eur Geriatr Med
Yamagiwa D, Katayama O, Yamaguchi R, Akaida S, Makino K, Shimada H.   +5 more
europepmc   +1 more source

Impact of growth mode, phase, and rate on the metabolic state of the extremely thermophilic archaeon Pyrococcus furiosus

, 2017
Piyum A. Khatibi, Chung‐Jung Chou, Andrew J. Loder, Jeffrey V. Zurawski, Michael W. W. Adams, Robert M. Kelly   +5 more
openalex   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Cerebral Metabolic Rate of Oxygen and Accelerometry-Based Fatigability in Community-Dwelling Older Adults. [PDF]

Aging Cell
Gay EL, Rosano C, Coen PM, Bohnen N, Huppert T, Qiao YS, Glynn NW.   +6 more
europepmc   +1 more source

Basal metabolic rate in migratory waders: intra‐individual, intraspecific, interspecific and seasonal variation [PDF]

, 2001
Anders Kvist, Åke Lindström
openalex   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Life in the slowest lane: Feeding allometry lowers metabolic rate scaling in the largest whales. [PDF]

Sci Adv
Blawas AM, Videsen SKA, Cade DE, Calambokidis J, Friedlaender AS, Johnston DW, Madsen PT, Goldbogen JA.   +7 more
europepmc   +1 more source