Results 231 to 240 of about 2,197,729 (354)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Intra-Seasonal Flexibility in Avian Metabolic Performance Highlights the Uncoupling of Basal Metabolic Rate and Thermogenic Capacity

, 2013
Magali Petit, Agnès Lewden, François Vézina   +2 more
openalex   +2 more sources

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Association between basal metabolic rate and cognitive function in Chinese older adults: the mediating effect of sarcopenia. [PDF]

BMC Geriatr
Ding H, Zhang L, Ma C, Shao Z, Zhao X, Li C.   +5 more
europepmc   +1 more source

Is there an association between body composition, basal metabolic rate, and sleep in elderly patients with and without obstructive sleep apnea?

, 2013
Rita Boscolo, Andrea Maculano Esteves, Marcos Gonçalves Santana, Valter Antônio Rocha Viana, Viviane Grassmann, Sérgio Tufik, Marco Túlio de Mello   +6 more
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

MRI-based quantification of whole-organ renal metabolic rate of oxygen during free-breathing. [PDF]

Magn Reson Med
Kamona N, Langham MC, Deshpande RS, Vu BD, Hosseini M, Dennison J, Jaroszynski KM, Wehrli FW.   +7 more
europepmc   +1 more source

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

Thermal effects on metabolic rate in diapausing <i>Pieris rapae</i> butterflies. [PDF]

Curr Res Insect Sci
Mikucki EE, Julick C, Buchanan JL, Montooth KL, Lockwood BL.   +4 more
europepmc   +1 more source

Classification of metabolic syndrome subjects and marathon runners with the k-means algorithm using heart rate variability features

, 2016
Gilberto Perpiñán, Érika Severeyn, Miguel Altuve, Sara Wong   +3 more
openalex   +2 more sources