Results 241 to 250 of about 5,645,921 (292)

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

Atomic Layer Deposition Processes: Versatile Platforms for Engineering ZnO‐Chitosan Biointerfaces

Advanced Healthcare Materials, EarlyView.
Vapour phase metalation (VPM), multiplied pulsed vapour phase infiltration (MPI), and O2 plasma‑enhanced atomic layer deposition (PEALD) tailor Zn–chitosan (Zn‑CS) films. PEALD improves wettability and biocompatibility. MPI enhances semiconductor behavior. Antiseptic selectivity: VPM → E. coli; MPI → H. pylori.
Mabel Moreno, Anjana Devi, David Zanders, Miryam Arredondo, Davide Mariotti, Ruairi McGlynn, Sindy Devis, Simón Guerrero, Eglantina Benavente, Matias Alegría, Yusser Olguin, Lorena Lobos‐Gonzalez, Kevin Guzmán, Elizabeth Rivas‐Yañez, Paula Solar, Valentin Cepus, Michael Krause, Luis Velásquez   +17 more
wiley   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

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Genetics of metabolic resistance.

Mathematical Biosciences, 2016
Herbicide resistance has become a major issue for many weeds. Metabolic resistance refers to the biochemical processes within organisms that degrade herbicides to less toxic compounds, resulting in a shift of the dose response curve. This type of resistance involves polygenic inheritance.
O. Richter, D. Langemann, R. Beffa
semanticscholar   +3 more sources

Risk of resistance and the metabolic resistance mechanism of Laodelphax striatellus (Fallén) to cyantraniliprole.

Pesticide Biochemistry and Physiology, 2023
Cyantraniliprole is a highly effective diamide insecticide used to control of Laodelphax striatellus (Fallén). This study aimed to assess the insecticide resistance risk of L. striatellus and its metabolic resistance mechanisms.
Zhaoge Li, Xueting Wang, Longzhi Guo, Tao Yin, Dongmei Liu, Shuang Liu, Xingmei You, Xiaoming Xia   +7 more
semanticscholar   +1 more source

The metabolic syndrome: Insulin resistance

Current Hypertension Reports, 2009
Insulin resistance is the most accepted unifying theory explaining the pathophysiology of the metabolic syndrome. However, epidemiologic studies indicate that a substantial proportion of patients with the metabolic syndrome do not have evidence of insulin resistance, and the correlation between insulin resistance and individual components of the ...
Nasser Mikhail
exaly   +3 more sources

CYP81A68 confers metabolic resistance to ALS and ACCase-inhibiting herbicides and its epigenetic regulation in Echinochloa crus-galli.

Journal of Hazardous Materials, 2022
Long-term and excessive herbicide use has led to some environmental concerns and especially, herbicide resistance evolution in weeds. Here, we confirmed acetolactate synthase (ALS) inhibiting herbicide penoxsulam resistance and cross resistance to acetyl-
Lang Pan, Qiushuang Guo, Junzhi Wang, Li Shi, X. Yang, Yaoyu Zhou, Q. Yu, L. Bai   +7 more
semanticscholar   +1 more source

Resistance to obesity and resistance to atherosclerosis: Is there a metabolic link?

Nutrition, Metabolism and Cardiovascular Diseases, 2007
This review deals with the question whether resistance to obesity affects resistance to atherosclerosis.Resistance to diet-induced obesity in inbred mouse strains involves an adequate response to Leptin, the main regulator of the energy balance cycle.
Olga, Stein, Yechezkiel, Stein
openaire   +2 more sources

Myocardial Resistance to Metabolic Acidosis

Archives of Surgery, 1966
SOME OF the cardiovascular problems and difficulties in resuscitation occurring during shock, massive transfusions, hypothermia, and the postcardiac arrest period have been attributed to the myocardial depressant effects of the concomittant metabolic acidosis.
N Y, Smith, A N, Corbascio
openaire   +2 more sources

Metabolic mechanisms of antibiotic resistance

Nature Reviews Genetics, 2021
In a study in Science, Lopatkin et al. identify mutations in metabolic genes of Escherichia coli that lead to antibiotic resistance. Functional analyses of the mutations support the view that metabolic dysfunction helps pathogens escape the lethal effects of antibiotics.
openaire   +2 more sources