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Membrane vesicles derived from the probiotic Lacticaseibacillus casei BL23 demonstrate antimicrobial properties against Escherichia coli and a potential biological effect in improving the overall survival of C. elegans infected with Pseudomonas aeruginosa. These vesicles stimulated immune responses in primary cells without causing toxicity. Our results
Cecilia L. D'Antoni +11 more
wiley +1 more source
Metabolic syndrome and ADRB3 gene polymorphism in severely obese patients from South Italy [PDF]
C Finelli +9 more
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Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa +8 more
wiley +1 more source
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
Metabolic reprogramming-a breakthrough point in overcoming resistance to BRAF mutant melanoma targeted therapy (Review). [PDF]
Zhao X, Chen F, Li H.
europepmc +1 more source
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Genetics of metabolic resistance
Mathematical Biosciences, 2016Herbicide resistance has become a major issue for many weeds. Metabolic resistance refers to the biochemical processes within organisms that degrade herbicides to less toxic compounds, resulting in a shift of the dose response curve. This type of resistance involves polygenic inheritance.
Richter, Otto +2 more
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Myocardial Resistance to Metabolic Acidosis
Archives of Surgery, 1966SOME OF the cardiovascular problems and difficulties in resuscitation occurring during shock, massive transfusions, hypothermia, and the postcardiac arrest period have been attributed to the myocardial depressant effects of the concomittant metabolic acidosis.
N Y, Smith, A N, Corbascio
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Metabolic mechanisms of antibiotic resistance
Nature Reviews Genetics, 2021In a study in Science, Lopatkin et al. identify mutations in metabolic genes of Escherichia coli that lead to antibiotic resistance. Functional analyses of the mutations support the view that metabolic dysfunction helps pathogens escape the lethal effects of antibiotics.
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Carbohydrate Metabolism in Shock Resistance
1973At the annual meeting of the Hungarian Society of Physiological Sciences (1970) we reported on the results of our earlier investigation dealing with the carbohydrate metabolism in shock. It has been shown by Karady et al., (1948, 1961) that numerous changes found in shock do not occur or are modified in the so-called “stage of resistance”. Therefore it
A, Bardoczi, J, Arokszallasi, S, Karady
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