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Carbohydrate Metabolism in Shock Resistance
1973At the annual meeting of the Hungarian Society of Physiological Sciences (1970) we reported on the results of our earlier investigation dealing with the carbohydrate metabolism in shock. It has been shown by Karady et al., (1948, 1961) that numerous changes found in shock do not occur or are modified in the so-called “stage of resistance”. Therefore it
A, Bardoczi, J, Arokszallasi, S, Karady
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Insulin resistance and lipoprotein metabolism
Current Opinion in Lipidology, 1995Dyslipidaemia in insulin resistance comprises elevated plasma triglycerides, decreased HDL, a preponderance of small, dense LDL and increased postprandial lipaemia. In terms of cause and effect, small, dense LDL, alimentary hyperlipidaemia and changes in HDL are consequences of elevated triglycerides.
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The metabolic syndrome: Insulin resistance
Current Hypertension Reports, 2009Insulin resistance is the most accepted unifying theory explaining the pathophysiology of the metabolic syndrome. However, epidemiologic studies indicate that a substantial proportion of patients with the metabolic syndrome do not have evidence of insulin resistance, and the correlation between insulin resistance and individual components of the ...
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Cholesterol metabolism in hypercholesterolemia-resistant rabbits
Atherosclerosis, 1991Normal rabbits typically respond to a diet high in cholesterol with a large increase in the concentration of plasma cholesterol. We have previously described the breeding and partial characterization of a variant rabbit which does not respond to a high cholesterol diet with changes in plasma cholesterol concentration.
D S, Loose-Mitchell +6 more
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Insulin, Cation Metabolism and Insulin Resistance
Journal of Basic and Clinical Physiology and Pharmacology, 1998There is considerable evidence that insulin and insulin-like growth factors regulate a number of important physiological functions in a variety of tissues, some not considered to be classically insulin sensitive. Impaired biological responses to insulin and related insulin-like growth factors are referred to as insulin resistance.
J R, Sowers, B, Draznin
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Insulin Resistance, Carbohydrate Metabolism, and Hypertension
American Journal of Hypertension, 1991Hypertension and diabetes are common diseases in Westernized civilizations, and in the United States, the frequency of both diseases is increasing as the society ages. Factors contributing to the high prevalence and increasing frequency of these diseases include obesity, hyperinsulinemia and insulin resistance, genetic factors, and abnormal cellular ...
J R, Sowers +4 more
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Insulin resistance and lipid metabolism
The American Journal of Cardiology, 1999The 3 major components of the dyslipidemia of insulin resistance are increased triglyceride levels, decreased high-density lipoprotein (HDL) cholesterol, and changes in the composition of low-density lipoprotein (LDL) cholesterol. Hyperinsulinemia and the central obesity that typically accompanies insulin resistance are thought to lead to ...
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Carbohydrate Metabolism, Insulin Resistance, and Metabolic Cardiovascular Syndrome
Journal of Cardiovascular Pharmacology, 1992Insulin resistance is seen in several pathophysiological conditions, such as obesity, diabetes mellitus, and essential hypertension. This means that a greater than normal amount of insulin is needed to give a normal biological response. A major biochemical defect in insulin resistance seems to be a defect in the intracellular nonoxidative metabolism of
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Science, 2019
Metabolism Once imported into cells and phosphorylated, the glucose analog 2-deoxyglucose (2DG) inhibits glycolysis. As glycolysis is up-regulated in many cancers, 2DG has been proposed as a treatment. Using yeast as a model, Defenouillere et al. investigated how cells become resistant to 2DG.
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Metabolism Once imported into cells and phosphorylated, the glucose analog 2-deoxyglucose (2DG) inhibits glycolysis. As glycolysis is up-regulated in many cancers, 2DG has been proposed as a treatment. Using yeast as a model, Defenouillere et al. investigated how cells become resistant to 2DG.
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Metabolic responses during hydraulic resistance exercise
Medicine & Science in Sports & Exercise, 1987Thirteen college-age men under-went a treadmill (TM)-graded VO2max exercise test on 1 d and a 24.5-min hydraulic resistive exercise circuit on a following day. Seven exercises were performed in the following order: leg extension, bent-over row, bicep curl, squat, upright row, bench press, and behind-neck press.
D L, Ballor, M D, Becque, V L, Katch
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