Results 1 to 10 of about 100,418 (155)

Metabolic Syndrome [PDF]

Medicine, 2003
The metabolic syndrome is characterized by diabetes mellitus, obesity, hypertension, hyperlipidaemia and polycystic ovary syndrome. The lipid profiles of patient with metabolic syndrome is often characterized by the appearance of hypertrygliceridaemia and small, dense LDL-cholesterol, together with low HDL-cholesterol. Patients with these abnormalities
Thang S. Han, Michael E.J. Lean
  +8 more sources

The metabolic syndrome [PDF]

Journal of the Royal Society of Medicine, 2006
The metabolic syndrome (sometimes also known as syndrome X or insulin resistance syndrome) has been recognized since the late 1980s, arguably long before, and at the time of writing, there are at least five published definitions of it. Most recently the International Diabetes Federation has proposed ‘...
André C. Carpentier, Tamas Fulop, Daniel Tessier   +2 more
openaire   +5 more sources

Targeting transforming growth factor beta (TGF-β) using Pirfenidone, a potential repurposing therapeutic strategy in colorectal cancer

Scientific Reports, 2023
The modulating factors within the tumor microenvironment, for example, transforming growth factor beta (TGF-β), may limit the response to chemo and immunotherapy protocols in colorectal cancer (CRC).
Hamid Jamialahmadi, Seyedeh Elnaz Nazari, Hamid TanzadehPanah, Ehsan Saburi, Fereshteh Asgharzadeh, Fatemeh Khojasteh-Leylakoohi, Maryam Alaei, Mahdi Mirahmadi, Fatemeh Babaei, Seyedeh Zahra Asghari, Saeide Mansouri, Ghazaleh Khalili-Tanha, Mina Maftooh, Hamid Fiuji, Seyed Mahdi Hassanian, Gordon A. Ferns, Majid Khazaei, Amir Avan   +17 more
doaj   +1 more source

Machine learning algorithms reveal potential miRNAs biomarkers in gastric cancer

Scientific Reports, 2023
Gastric cancer is the high mortality rate cancers globally, and the current survival rate is 30% even with the use of combination therapies. Recently, mounting evidence indicates the potential role of miRNAs in the diagnosis and assessing the prognosis ...
Hanieh Azari, Elham Nazari, Reza Mohit, Alireza Asadnia, Mina Maftooh, Mohammadreza Nassiri, Seyed Mahdi Hassanian, Majid Ghayour-Mobarhan, Soodabeh Shahidsales, Majid Khazaei, Gordon A. Ferns, Amir Avan   +11 more
doaj   +1 more source

Down regulation of Cathepsin W is associated with poor prognosis in pancreatic cancer

Scientific Reports, 2023
Pancreatic ductal adenocarcinoma (PDAC) is associated with a very poor prognosis. Therefore, there has been a focus on identifying new biomarkers for its early diagnosis and the prediction of patient survival.
Fatemeh Khojasteh-Leylakoohi, Reza Mohit, Nima Khalili-Tanha, Alireza Asadnia, Hamid Naderi, Ghazaleh Pourali, Zahra Yousefli, Ghazaleh Khalili-Tanha, Majid Khazaei, Mina Maftooh, Mohammadreza Nassiri, Seyed Mahdi Hassanian, Majid Ghayour-Mobarhan, Gordon A. Ferns, Soodabeh Shahidsales, Alfred King-yin Lam, Elisa Giovannetti, Elham Nazari, Jyotsna Batra, Amir Avan   +19 more
doaj   +1 more source

The metabolic syndrome

Nursing Standard, 2003
Prevention of disease rather than its alleviation or cure has always been the aim of healthcare professionals. While this goal has been achieved for many infectious diseases through improvements in hygiene and vaccination, as well as for acute deficiency diseases such as scurvy, less progress has been made with chronic diseases. These are increasing as
Gries Fa, Liebermeister H
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Therapeutic Potential of Hydrogen-Rich Water on Muscle Atrophy Caused by Immobilization in a Mouse Model

Pharmaceuticals, 2023
Skeletal muscle atrophy is associated with poor quality of life and disability. Thus, finding a new strategy for the prevention and treatment of skeletal muscle atrophy is very crucial.
Seyedeh Elnaz Nazari, Alex Tarnava, Nima Khalili-Tanha, Mahdieh Darroudi, Ghazaleh Khalili-Tanha, Amir Avan, Majid Khazaei, Tyler W. LeBaron   +7 more
doaj   +1 more source

Diagnostic Value of CK19, HBME-1 and TROP2 Biomarkers in Identification of Different Types of Thyroid Follicular Neoplasms

Acta Medica Iranica, 2021
Thyroid malignancies are found in 7% to 15% of all thyroid nodules. Immunohistochemical markers, including CK19, HBME-1and TROP2, have shown an effective role in identifying these malignancies.
Masoud Mohebbi, Shohreh Vojuhi, Zohreh Mousavi, Mohammadali Yaghoubi, Reza Ziaolhagh   +4 more
doaj   +1 more source

The Metabolic Syndrome [PDF]

Endocrine Reviews, 2008
The "metabolic syndrome" (MetS) is a clustering of components that reflect overnutrition, sedentary lifestyles, and resultant excess adiposity. The MetS includes the clustering of abdominal obesity, insulin resistance, dyslipidemia, and elevated blood pressure and is associated with other comorbidities including the prothrombotic state, proinflammatory
Marc-Andre Cornier, Rachael E. Van Pelt, Rachel C. Lindstrom, Amy J. Steig, Teri L. Hernandez, Dana Dabelea, Robert H. Eckel, Nicole R. Stob, Hong Wang   +8 more
openaire   +3 more sources

Bioinformatics analysis and machine learning approach applied to the identification of novel key genes involved in non-alcoholic fatty liver disease

Scientific Reports, 2023
Non-alcoholic fatty liver disease (NAFLD) comprises a range of chronic liver diseases that result from the accumulation of excess triglycerides in the liver, and which, in its early phases, is categorized NAFLD, or hepato-steatosis with pure fatty liver.
Elham Nazari, Ghazaleh Khalili-Tanha, Alireza Asadnia, Ghazaleh Pourali, Mina Maftooh, Majid Khazaei, Mohammadreza Nasiri, Seyed Mahdi Hassanian, Majid Ghayour-Mobarhan, Gordon A. Ferns, Mohammad Ali Kiani, Amir Avan   +11 more
doaj   +1 more source