Results 161 to 170 of about 4,485,385 (359)

Imaging of Lipid Droplets in Living Cells and Mice with Metabolic Dysfunction‐Associated Steatotic Liver Disease via a Galactose‐Modified Supramolecular Near‐Infrared Fluorescent Glycoprobe

Advanced Functional Materials, EarlyView.
A galactose‐modified supramolecular near‐infrared (NIR) glycoprobe, TCF‐FBN@Gal‐BSA, enables targeted delivery to the liver through the asialoglycoprotein receptor (ASGPR) and facilitates liver‐targeting fluorescence visualization of lipid droplets (LDs) in metabolic dysfunction‐associated steatotic liver disease (MASLD) mice.
Han‐Min Wang, Lei Dong, Qiu‐Lian Hao, Lu‐Lu Sun, Xin‐Rong Li, Yu‐Wei Yuan, Ming‐Ye Tang, Jin Gong, Yi Zang, Jia Li, Tony D. James, Xiao‐Peng He, Hai‐Hao Han   +12 more
wiley   +1 more source

Cardio metabolic risk factors for atrial fibrillation in type 2 diabetes mellitus: Focus on hypertension, metabolic syndrome and obesity [PDF]

, 2019
Objective. Atrial fibrillation (AF) in type 2 diabetes mellitus (T2DM) has been little explored so far. However, there are several cardio metabolic risk factors for AF in T2DM patients, such as arterial hypertension, obesity or the metabolic syndrome ...
Bratu, Ovidiu G., Cozma, Matei-Alexandru, Diaconu, Camelia C, Dobrica, Elena-Codruta, Epingeac, Mirela-Elena, Gaman, Amelia M., Gaman, Mihnea-Alexandru, Pantea Stoian, Anca M., Pascu, Emilia G.   +8 more
core   +1 more source

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

Advanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras, Saahil S. Baghel, Rune F. Jensen, Aneesh Thakur, Henrik Franzyk, Oskar Thofte, Marco Herrera‐Barrera, Madeleine Landry, Melike Ongun, Ahmad Tami, Marlene P. Thanthrige, Eva Callens, Corinne Beinat, Thomas Rades, Søren R. Paludan, Kristian Riesbeck, Ida Rosenkrands, Dennis Christensen, Gabriel K. Pedersen, Camilla Foged   +19 more
wiley   +1 more source

Brain histaminergic system: An emerging target for the treatment of feeding and eating-related disorders

Pharmacological Research
Feeding is an intrinsic and fundamental behavior regulated by complex neurobiological networks that integrate peripheral metabolic signals with neurotransmitter systems within key brain regions.
Alessia Costa, Emanuela Micioni Di Bonaventura, Luca Botticelli, Barbara Eramo, Silvana Gaetani, Maria Beatrice Passani, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura, Gustavo Provensi   +8 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

The association between age at menarche (AAM) and cardiovascular disease (CVD) risk factors in the MASHAD cohort study

Scientific Reports
Age at menarche may be associated with cardiovascular disease risk factors in different ethnic groups. The purpose of this study was to identify the association of cardiovascular disease (CVD) risk factors with age at menarche (AAM) in Mashhad, the ...
Niloofar Shabani, Sara Saffar Soflaei, Khadijeh Bavafa-Valenlia, Nayereh Esmaeilzadeh, Maryam Mohammadi-Bajgriran, Zahra Namazibaygi, Mohsen Moohebati, Gordon A. Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan   +9 more
doaj   +1 more source

Influence of Ischemic Preconditioning Before Exercise on Performance and Blood Pressure in Men with Metabolic Syndrome

, 2022
Vadim V. Sverchkov, Е. В. Быков
openalex   +1 more source

Essential Role of Granulosa Cell Glucose and Lipid Metabolism on Oocytes and the Potential Metabolic Imbalance in Polycystic Ovary Syndrome [PDF]

, 2023
Chen-Hua Zhang, Xiangyi Liu, Jing Wang
openalex   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Age-related frequency of the metabolic syndrome in type 2 diabetic patients [PDF]

, 2012
People with metabolic syndrome are at increased risk for developing diabetes mellitus. The present study aimed to assess the age related metabolic syndrome of patients diagnosed with type 2 diabetes mellitus.
Marjani, A.
core