Results 231 to 240 of about 4,435,982 (345)

Neutrophil‐Driven Cascade‐Targeted Nanocarriers Restore Mitochondrial Homeostasis to Ameliorate Renal Ischemia–Reperfusion Injury

Advanced Science, EarlyView.
A neutrophil‐mediated dual‐targeting liposome (NKN‐LNP) is developed to treat renal ischemia–reperfusion injury. The system enables spatiotemporally controlled delivery of NMN to injured tubules via MMP‐2/9 activation and KIM1 recognition, restoring mitochondrial function through NAD+‐SIRT3 signaling and preventing the transition from acute kidney ...
Hangbin Ma, Yang Li, Shen Lin, Feifan Chu, Gaozhan Ren, Yinhui Mao, Mingzhi Wu, Yuning Ma, Qiwei Ji, Zujie Chen, Jinzhong Ji, Mingxin Sun, Yongpeng Xu, Xiaoli Sun, Longguang Tang, Hao Zhou   +15 more
wiley   +1 more source

Genomic Structural Equation Modeling Reveals Cardiovascular-Kidney-Metabolic Syndrome Genetic Architecture. [PDF]

J Diabetes
Lu C, Li L, Chen J, Chang R, Dong H.
europepmc   +1 more source

Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition.

Cell Metabolism, 2017
R. Kootte, E. Levin, J. Salojärvi, L. Smits, Annick V. Hartstra, S. D. Udayappan, Gerben D. A. Hermes, K. Bouter, Annefleur M. Koopen, J. Holst, F. Knop, E. Blaak, J. Zhao, H. Smidt, A. Harms, Thomas Hankemeijer, J. Bergman, H. Romijn, F. Schaap, S. O. Olde Damink, M. Ackermans, G. Dallinga-Thie, E. Zoetendal, W. D. de Vos, M. Serlie, E. Stroes, A. Groen, M. Nieuwdorp   +27 more
semanticscholar   +1 more source

METABOLIC SYNDROME AND ITS COMPONENTS IN PATIENTS WITH ACUTE CORONARARY SYNDROME AT BPKIHS, A TERTIARY CARE CENTER IN NEPAL

, 2016
Pandey NK, Karki.P Dhungana, Kunjang Sherpa   +2 more
openalex   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

Social deprivation, race, and metabolic syndrome in patients with polycystic ovary syndrome. [PDF]

J Endocr Soc
Lee IT, King S, Sealy N, Rees J, Mumford SL, Hinkle SN, Dokras A.   +6 more
europepmc   +1 more source

Effect of non-dipper and dipper blood pressure patterns on Tp-Te interval and Tp-Te/QT ratio in patients with metabolic syndrome.

, 2014
Kemal Karaağaç, Erhan Tenekecioğlu, Osman Can Yontar, Mustafa Kuzeytemiz, Fahriye Vatansever, Ahmet Tütüncü, Özlem Arıcan Özlük, Mustafa Yılmaz, Mehmet Demir   +8 more
openalex  

Association Metabolic Syndrome with Sarcopenia in Korean Stroke Patients : Korean National Health and Nutrition Examination Survey Data(2008-2011)

, 2018
Sook-Hee Choi, Yun‐Hee Kim
openalex   +2 more sources

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Metabolic syndrome and cholangiocarcinoma: large numbers, small risks, but big implications. [PDF]

Hepatobiliary Surg Nutr
Saeed U, Yaqub S.
europepmc   +1 more source