Advanced Science, EarlyView.Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao +13 more
wiley +1 more source
Acylcarnitines Are Associated with Metabolic Syndrome and Hypertension in Two Contrasted Obese Populations. [PDF]
NutrientsChabi N +10 more
europepmc +1 more source
Bilirubin as a Modulator of WNK1 Protein Signaling: Implications for Neuroinflammatory Diseases
Advanced Science, EarlyView.ABSTRACT Previously regarded merely as a potentially harmful waste product of heme catabolism, bilirubin has now emerged as a pleiotropic molecule with potent antioxidant, anti‐inflammatory, and hormone‐like properties. Recent findings have revealed protective effects against cardiovascular, metabolic, autoimmune, and neoplastic diseases, as well as ...
Sri Jayanti +3 more
wiley +1 more source
A Comprehensive Analysis of the Impact of Nutrient Intakes on the Stages and Mortality of Cardiovascular-Kidney-Metabolic Syndrome. [PDF]
Food Sci NutrQing J +6 more
europepmc +1 more source
Do diabetes, metabolic syndrome or their association equally affect biventricular function? A tissue Doppler study [PDF]
, 2012 Francesco Paneni +9 more
openalex +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
The role of metabolic syndrome in osteoarthritis development: Is obesity the key driver? [PDF]
Osteoarthr Cartil OpenAndrea D +5 more
europepmc +1 more source
The Mini Nutritional Assessment combined with body fat for detecting the risk of sarcopenia and sarcopenic obesity in metabolic syndrome [PDF]
Chi‐Hua Yen +3 more
openalex +1 more source
Metabolic Syndrome: A Marker for Decreased Cumulative Patency Among Patients Undergoing Arteriovenous Fistula Placement [PDF]
, 2012 Clinton D. Protack +6 more
openalex +1 more source
Advanced Science, EarlyView.ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu +15 more
wiley +1 more source