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[Metabolic syndrome and the X of question].

Arquivos brasileiros de endocrinologia e metabologia, 2007
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Hypothalamic Origin of the Metabolic Syndrome X

Annals of the New York Academy of Sciences, 1999
ABSTRACT:The conspicuous similarities between Cushing's syndrome and the Metabolic Syndrome X open up the possibility that hypercortisolemia is involved also in the latter. Salivary cortisol is possible to measure during undisturbed conditions including perceived stressful events during everyday life.
P, Björntorp, R, Rosmond
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Cardiac syndrome X versus metabolic syndrome X

International Journal of Cardiology, 2007
In 1973, Kemp [1], in an editorial, introduced the term ‘syndrome X’ to indicate the uncertain etiology of chest pain in patients who had a positive exercise ECG suggestive of myocardial ischemia but on coronary arteriograms had normal coronary arteries.
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Thymidylate metabolism in fragile X syndrome cells

Somatic Cell and Molecular Genetics, 1985
The observation that decreased thymidylate supply in vitro induces the expression of the Xq27 chromosome fragile site prompted us to examine cellular thymidylate metabolism. Using a sensitive enzyme assay for deoxyribonucleotide triphosphates, we found that the total cellular thymidine triphosphate pools in cell lines from fragile X patients and ...
J C, Wang, R W, Erbe
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Cyclic AMP metabolism in fragile X syndrome

Annals of Neurology, 1992
AbstractCyclic AMP (cAMP) metabolism was studied in platelets from a series of 14 patients with fragile X syndrome (fra X) and 21 control individuals. 1‐Isobutyl‐3‐methylxanthine was used to inhibit phosphodiesterase and thus measure cAMP production, prostaglandin E1 was used to assess receptor‐mediated cAMP accumulation, and forskolin was used to ...
E, Berry-Kravis, P R, Huttenlocher
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Steroid metabolism in Metabolic Syndrome X

Best Practice & Research Clinical Endocrinology & Metabolism, 2001
Preceding chapters in this volume describe relatively rare conditions associated with qualitative rather than quantitative changes in enzymes involved in steroid synthesis and metabolism. In this chapter, several examples show how more subtle variations in activities of the same enzymes may be important in the pathophysiology of common diseases of ...
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Retinoid X Receptor Heterodimers in the Metabolic Syndrome

New England Journal of Medicine, 2005
The principal abnormalities of the metabolic syndrome are abdominal obesity, atherogenic dyslipidemia, hypertension, insulin resistance, inflammation, and prothrombotic states.
Andrew I, Shulman, David J, Mangelsdorf
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Metabolic syndrome X: An inflammatory condition?

Current Hypertension Reports, 2004
Obesity, atherosclerosis, insulin resistance and hyperinsulinemia, hyperlipidemia, essential hypertension, type 2 diabetes mellitus, and coronary heart disease (CHD) are the components of metabolic syndrome X and are associated with elevated plasma levels of C-reactive protein, interleukin-6, and tumor necrosis factor-alpha, which are markers of ...
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The Metabolic Syndrome X And Peripheral Cortisol Synthesis

Experimental and Clinical Endocrinology & Diabetes, 2002
The metabolic syndrome X and Cushing's syndrome show similar symptoms but one major difference: Plasma cortisol is not elevated in the metabolic syndrome. Evidence is presented, that by the action of 11 beta-hydroxysteroid dehydrogenase 1 (11 beta HSD1) higher intracellular cortisol concentration may be created that may be relevant to induce insulin ...
V, Bähr, A F, Pfeiffer, S, Diederich
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Low-flow vascular remodeling in the metabolic syndrome X

American Journal of Physiology-Heart and Circulatory Physiology, 2004
Peripheral microvascular dysfunction is a common affliction in patients with the metabolic syndrome X. Previous studies have described a number of vascular impairments in vasomotor control in both human patients and animal models of syndrome X, but the net effect of these impairments on microvascular structure has not been examined.
David W, Stepp, David M, Pollock, Jefferson C, Frisbee   +2 more
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