Results 161 to 170 of about 57,504 (328)

Plasma C24:0- and C26:0-lysophosphatidylcholines are reliable biomarkers for the diagnosis of peroxisomal β-oxidation disorders

open access: yesJournal of Lipid Research
The gold-standard diagnostic test for peroxisomal disorders (PDs) is plasma concentration analysis of very long-chain fatty acids (VLCFAs). However, this method’s time-consuming nature and limitations in cases which present normal VLCFA levels ...
Blai Morales-Romero   +9 more
doaj  

The Transcriptome Trajectory Reveals Sex‐ and Age‐Dependent Changes in the Mouse Adrenal Gland

open access: yesAging Cell, EarlyView.
This comprehensive RNA‐seq dataset reveals the sex‐ and age‐dependent gene expression profile of the mouse adrenal gland. It helps identify novel marker genes of the adrenal inner cortex, offering new insights into the organ's development and aging process.
Hui Wang   +4 more
wiley   +1 more source

Skeletal Maturity and Age‐Related Changes in Immune Cells and Circulatory Factors Impair Large‐Scale Bone Regeneration

open access: yesAging Cell, EarlyView.
Although the ribs are the only human bones capable of regenerating large‐scale defects, this remarkable ability declines with skeletal maturity and age. Here, we reproduce skeletal maturity and age‐related phenotypic changes in a mouse model of rib resection.
Luciana Yamamoto de Almeida   +15 more
wiley   +1 more source

Progeny, December 2003, Vol. 19, no. 4 [PDF]

open access: yes, 2003
This newsletter from The Department of Public Health about perinatal health care and ...

core  

Rapamycin Does Not Compromise Exercise‐Induced Muscular Adaptations in Female Mice

open access: yesAging Cell, EarlyView.
Rapamycin is largely compatible with the physical and skeletal muscle benefits of progressive weighted wheel running (PoWeR). The detrimental effects of rapamycin on glucose metabolism in the context of voluntary exercise are mitigated by intermittent dosing.
Christian J. Elliehausen   +9 more
wiley   +1 more source

Rat models of fetal alcohol spectrum disorders for studying the critical role of cerebellar damage: A scoping review

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
In rat models used to study the effects of early alcohol exposure on cerebellum function and structure during pregnancy and lactation, the following conclusions can be drawn: (1) Exposure to ethanol during the first and second‐trimester equivalent in humans affects biochemical pathways in the cerebellum, but produces fewer structural changes.
Fátima Nogales   +5 more
wiley   +1 more source

Clinical periodontal diagnosis

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi   +5 more
wiley   +1 more source

The aporetic dialogues of Modena on gender differences: Is it all about testosterone? EPISODE I: CRIME

open access: yesAndrology, EarlyView.
Abstract This is the first episode of a series of four discussions on the differences between males and females, in apparently non‐andrological fields. You will read the transcript of discussions that actually took place at the Endocrinology Unit in Modena, Italy, in the form of the aporetic dialogues of ancient Greece.
Giulia Brigante   +7 more
wiley   +1 more source

CNTF protects oligodendrocytes from ammonia toxicity: Intracellular signaling pathways involved

open access: yesNeurobiology of Disease, 2009
In pediatric patients, hyperammonemia can provoke irreversible damages to developing CNS like cortical atrophy, ventricular enlargement, demyelination or gray and white matter hypodensities which are concordant with alterations of neurons and ...
Laurène Cagnon, Olivier Braissant
doaj  

Role of caspases, calpain and cdk5 in ammonia-induced cell death in developing brain cells

open access: yesNeurobiology of Disease, 2008
Hyperammonemia in neonates and infants causes irreversible damages in the developing CNS due to brain cell loss. Elucidating the mechanisms triggering ammonia-induced cell death in CNS is necessary for the development of neuroprotective strategies.
Laurène Cagnon, Olivier Braissant
doaj  

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