Results 171 to 180 of about 2,371,969 (318)

The effect of trimethylamine N-oxide on the metabolism of visceral white adipose tissue in spontaneously hypertensive rat

, 2022
Guodong He, Xiaocong Liu, Xing-Hua Hou, Yingqing Feng   +3 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Comparative Metabolomic Approaches to Nanoplastic Toxicity in Mammalian and Aquatic Systems. [PDF]

Int J Mol Sci
Lee J, Jang H, Kim B, Jung J.
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Advances in the Regulatory Mechanism of Enzymes Involved in Soluble Sugar Metabolism in Fruits. [PDF]

Plants (Basel)
Meng Z, Li W, Huang G, Li X, Li R, Chen Y, Luo S, Guo L, Tang Y, Tang Y, Zhang Y, Ma X, Li L.   +12 more
europepmc   +1 more source

Dietary supplementation with freeze-dried Ampithoe sp. enhances the ammonia-N tolerance of Litopenaeus vannamei by reducing oxidative stress and endoplasmic reticulum stress and regulating lipid metabolism

, 2019
Teng Wang, Hongwei Shan, Zexing Geng, Yu Peng, Shen Ma   +4 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Relationship between impaired glucose metabolism and bone mineral density in patients with cystic fibrosis. [PDF]

Eur J Pediatr
Uçar M, Turan H, Kılıç Başkan A, Altun İ, Velioğlu Haşlak G, Karakaş H, Taşkın Z, Bingöl Aydın D, Güney AZ, Beşer ÖF, Kılınç Sakallı AA, Evliyaoğlu O, Bayramoğlu E.   +12 more
europepmc   +1 more source

The effect of renal impairment on the pharmacokinetics and metabolism of bopindolol. [PDF]

, 1991
N. J. Macdonald, AC Grant, RS Rodger, PA Meredith, HL Elliott   +4 more
openalex   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source