Results 221 to 230 of about 2,371,969 (318)

Metabolic Alterations Induced by a Seizure-Causing Sodium Channel Mutation and their Partial Normalization by Dietary α-Linolenic Acid in Drosophila. [PDF]

Neurochem Res
Kruth K, Kasuya J, Hand V, Iyengar A, Kitamoto T.   +4 more
europepmc   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Lipid metabolism abnormalities in pediatric abdominal solid malignant tumors: a comprehensive review. [PDF]

Front Pediatr
Hao Q, Han L, Mi W, Hu T, Lin A, Liu J.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Efficacy and Safety of PEGylated Recombinant Human Growth Hormone in Children With Growth Hormone Deficiency and Idiopathic Short Stature: A Real-World Cohort Study

International Journal of Endocrinology
Liping Ge, Canmiao Zhao, Yang Yang, Lijun Xu, Meiyuan Sun, Yanfang Su, Fang Xu, Qi Huang, Na Tao   +8 more
doaj   +1 more source

"Effect of agroecological and conventional farming systems on the metabolomic profile of yellow and red maize assessed by ¹H NMR". [PDF]

Food Chem X
Medina-Mendoza GG, Becerra-Martínez E, Noriega-Altamirano G, Castro-Arellano JJ, Camacho-Nieto O, Hidalgo-Martínez D, Cruz-Narváez Y.   +6 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

The metabolism of CYP2C9 and CYP2C19 for gliclazide by homology modeling and docking study

, 2008
Yuan Yao, Weiwei Han, Yihan Zhou, Ze‐Sheng Li, Qiang Li, Xiaoyan Chen, Dafang Zhong   +6 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Asparagine and Glutamine Metabolism in Chicks

, 1984
C.N. Coon, Rudi Balling
openalex   +1 more source