Results 231 to 240 of about 3,690,314 (381)
Decoding microglial immunometabolism: a new frontier in Alzheimer's disease research. [PDF]
Mol NeurodegenerJung ES, Choi H, Mook-Jung I.
europepmc +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
New insights into T cell metabolism in liver cancer: from mechanism to therapy. [PDF]
Cell Death DiscovXiao J, Liu T, Zeng F, Zhang J.
europepmc +1 more source
FEBS Open Bio, EarlyView.We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang +7 more
wiley +1 more source
COMPARATIVE STUDIES OF THE METABOLISM OF THE AMINO ACIDS
, 1931 Noel F. Shambaugh +2 more
openalex +1 more source
Role of metabolic transformation in cancer immunotherapy resistance: molecular mechanisms and therapeutic implications. [PDF]
Discov OncolShende S, Rathored J, Budhbaware T.
europepmc +1 more source
FEBS Open Bio, EarlyView.By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya +3 more
wiley +1 more source
Multimodal Metabolomic Analysis Reveals Novel Metabolic Disturbances in Adults With Early Treated Phenylketonuria. [PDF]
JIMD RepDos Santos Y +7 more
europepmc +1 more source
Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria
FEBS Open Bio, EarlyView.The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao +4 more
wiley +1 more source