Results 271 to 280 of about 5,419,102 (403)

Sphingolipids and their metabolism in physiology and disease

Nature reviews. Molecular cell biology, 2017
Y. Hannun, L. Obeid
semanticscholar   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Interactions between gut microbiota and parkinson's disease: the role of tryptophan metabolism. [PDF]

Cell Commun Signal
Fan X, Xiao Z, Chen Y, Yang H, Diao M, Hu W, Wang S.   +6 more
europepmc   +1 more source

The Effect of Daily Massive Doses of Viosterol upon Calcium and Phosphorus Metabolism and Blood Calcium and Inorganic Phosphorus in Calves

, 1934
C.W. Duncan, C.F. Huffman
openalex   +1 more source

THE METABOLISM OF THE PENICILLIA IN RELATION TO PENICILLIN BIOSYNTHESIS [PDF]

, 1956
H. R. V. Arnstein, P. T. Grant
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Evaluation of in vitro drug-drug interactions of ivermectin and antimalarial compounds. [PDF]

Malar J
Tipthara P, Kullasakboonsri R, Kobylinski KC, Tarning J.   +3 more
europepmc   +1 more source

One-Carbon Metabolism in Health and Disease.

Cell Metabolism, 2017
Gregory S. Ducker, J. Rabinowitz
semanticscholar   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Molecular interplay between TXNIP and GLUT9 underlies uric acid transport dysregulation in vitro under hyperuricemic stress. [PDF]

Eur J Med Res
Zhu Y, Zhang B, He Y, Du M, Chen W, Chen X, Yang Q, Kahaer M, Sun Y.   +8 more
europepmc   +1 more source