Results 281 to 290 of about 5,150,728 (333)
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Metabolism and Metabolic Effects of Thyroglobulin
Nature, 1957INJECTION of beef or hog thyroglobulin into experimental animals causes an increase in basal metabolic rate and antagonizes the action of antithyroid drugs. These effects are similar to those following the injection of thyroxine. There is yet no adequate explanation for the fact, reported by various workers1, that these thyroglobulins are more ...
Alister Craig +2 more
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Nature Reviews Cancer, 2013
Two recent papers have provided evidence that the mitochondrial sirtuin SIRT4 exerts tumour suppressive activities by repressing glutamine metabolism.
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Two recent papers have provided evidence that the mitochondrial sirtuin SIRT4 exerts tumour suppressive activities by repressing glutamine metabolism.
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Metabolism and Metabolic Effects of Alcohol
Medical Clinics of North America, 1984The author provides an excellent overview of the three major pathways for the metabolism of ethanol. Many of the toxic effects of ethanol can be attributed to two specific products, hydrogen and acetaldehyde, and these effects are explored in detail.
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Metabolism and Metabolic Regulation
2010The data available on GHR−/− at all ages. Glucose levels, which are very low in young animals, seem to normalize at older ages. Insulin levels remain significantly lower than normal throughout the lifespan of GHR−/− mice. Together, these data suggest that insulin sensitivity decreases only slightly as GHR−/− mice age.
Lucila Sackmann-Sala +2 more
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2014
Much has been learned about the metabolism and pharmacokinetics of ethanol through study of the enzymes participating in its metabolism, the effects of genetic variants in these enzymes on risk of alcoholism and ethanol pharmacokinetics, and pharmacokinetic modeling. Despite the short, well-characterized metabolic pathway and straightforward absorption
María Luz Cárdenas +1 more
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Much has been learned about the metabolism and pharmacokinetics of ethanol through study of the enzymes participating in its metabolism, the effects of genetic variants in these enzymes on risk of alcoholism and ethanol pharmacokinetics, and pharmacokinetic modeling. Despite the short, well-characterized metabolic pathway and straightforward absorption
María Luz Cárdenas +1 more
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Metabolic Fluxes and Metabolic Engineering
Metabolic Engineering, 1999Metabolic engineering is the directed improvement of cellular properties through the modification of specific biochemical reactions or the introduction of new ones, with the use of recombinant DNA technology. As such, metabolic engineering emphasizes metabolic pathway integration and relies on metabolic fluxes as determinants of cell physiology and ...
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Creatine and creatinine metabolism.
Physiological Reviews, 2000The goal of this review is to present a comprehensive survey of the many intriguing facets of creatine (Cr) and creatinine metabolism, encompassing the pathways and regulation of Cr biosynthesis and degradation, species and tissue distribution of the ...
M. Wyss, R. Kaddurah-Daouk
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Metabolism and metabolic effects of ketoacids
The American Journal of Clinical Nutrition, 1980Administration of any of the three branched-chain amino or ketoacids necessarily yields the respective aminated or deaminated compound because the ubiquitous enzyme, branched-chain amino acid transaminase, catalyzes the reversible transfer of amino groups between the three amino acids and their ketoacids. Branched-chain amino acid transaminase activity
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Current Rheumatology Reports, 2010
We consider recent developments in disorders affecting three areas of metabolism: glycogen, fatty acids, and the mitochondrial respiratory chain. Among the glycogenoses, new attention has been directed to defects of glycogen synthesis resulting in absence rather than excess of muscle glycogen ("aglycogenosis").
DiMauro S., Garone C., Naini A.
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We consider recent developments in disorders affecting three areas of metabolism: glycogen, fatty acids, and the mitochondrial respiratory chain. Among the glycogenoses, new attention has been directed to defects of glycogen synthesis resulting in absence rather than excess of muscle glycogen ("aglycogenosis").
DiMauro S., Garone C., Naini A.
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Trends in Biotechnology, 2010
Metabolic networks have been studied for several decades, and sophisticated computational frameworks are needed to augment experimental approaches to harness these complex networks. BNICE (Biochemical Network Integrated Computational Explorer), a computational approach for the discovery of novel biochemical pathways that is based on biochemical ...
Soh, Keng Cher, Hatzimanikatis, Vassily
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Metabolic networks have been studied for several decades, and sophisticated computational frameworks are needed to augment experimental approaches to harness these complex networks. BNICE (Biochemical Network Integrated Computational Explorer), a computational approach for the discovery of novel biochemical pathways that is based on biochemical ...
Soh, Keng Cher, Hatzimanikatis, Vassily
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