Results 291 to 300 of about 5,450,244 (405)

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

Nature, 2009
C. Cantó, Zachary Gerhart-Hines, J. Feige, Marie Lagouge, L. Noriega, J. Milne, P. Elliott, P. Puigserver, J. Auwerx   +8 more
semanticscholar   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Suppressing glutamine metabolism in the pancreatic cancer microenvironment can enhance the anti-tumor effect of CD8 T cells and promote the efficacy of immunotherapy. [PDF]

Front Immunol
Fan J, Chen J, Wang R, Peng Y, Tan S, Zhang X, Tang H, Chen M, Li B, Yang X.   +9 more
europepmc   +1 more source

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

Science, 2013
V. Ridaura, J. Faith, F. Rey, Jiye Cheng, A. Duncan, A. Kau, Nicholas W. Griffin, V. Lombard, B. Henrissat, J. Bain, M. Muehlbauer, O. Ilkayeva, C. Semenkovich, K. Funai, David K. Hayashi, B. Lyle, M. Martini, L. Ursell, J. Clemente, William W. Van Treuren, W. Walters, R. Knight, C. Newgard, A. Heath, J. Gordon   +24 more
semanticscholar   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

PORPHYRIN FORMATION AND HEMOGLOBIN METABOLISM IN CONGENITAL PORPHYRIA

, 1950
Irving M. London, Randolph West, David Shemin, D. Rittenberg   +3 more
openalex   +1 more source

ARNT2-driven transcriptional activation of STRA6 reprograms fatty acid metabolism to promote retroperitoneal liposarcoma progression. [PDF]

J Cancer Res Clin Oncol
Zhang J, Guo H, Ban B, Yang L, Lian J, Li G, Cai L, Deng K, Jiang H, Li X, Wang S.   +10 more
europepmc   +1 more source

Peroxisome proliferator-activated receptors: nuclear control of metabolism.

Endocrine reviews, 1999
B. Desvergne, W. Wahli
semanticscholar   +1 more source

Metabolic flexibility [PDF]

Nature Reviews Cancer, 2016
openaire   +3 more sources