Results 11 to 20 of about 985,469 (331)

Focus Issue on Metabolism: Metabolites, Metabolites Everywhere [PDF]

open access: yesPlant Physiology, 2015
Metabolic studies have arguably been conducted since the 13th century with Ibn al-Nafis stating that “the body and its parts are in a continuous state of dissolution and nourishment, so they are inevitably undergoing permanent change” ([Mahdi, 1974][1]).
Alisdair R, Fernie, Eran, Pichersky
openaire   +2 more sources

Quantification of a Novel Photosensitizer of Chlorin e6-C15-Monomethyl Ester in Beagle Dog Plasma Using HPLC: Application to Pharmacokinetic Studies

open access: yesMolecules, 2017
Chlorin e6-C15-monomethyl ester (CMME) is a novel photosensitizer, which is synthetized from the degradation products of silkworm excrement. Preclinical studies on the promising photosensitizer CMME are necessary to determine its therapeutic efficacy and
Xiuxiu Li   +5 more
doaj   +1 more source

Determination of the urinary aglycone metabolites of vitamin K by HPLC with redox-mode electrochemical detection [PDF]

open access: yes, 2005
We describe a method for the determination of the two major urinary metabolites of vitamin K as the methyl esters of their agyclone structures, 2-methyl-3-(3-3-carboxymethylpropyl)-1,4-naphthoquinone (5C-side-chain metabolite) and 2-methyl-3-(5-carboxy-3-
Edwards, C   +5 more
core   +1 more source

Free fatty acid receptor 1 stimulates cAMP production and gut hormone secretion through Gq-mediated activation of adenylate cyclase 2

open access: yesMolecular Metabolism, 2023
Objective: Free fatty acid receptor 1 (FFAR1) is highly expressed in enteroendocrine cells of the small intestine and pancreatic beta cells, where FFAR1 agonists function as GLP-1 and insulin secretagogues, respectively.
Jacob Emil Petersen   +9 more
doaj   +1 more source

Impact of limited solvent capacity on metabolic rate, enzyme activities, and metabolite concentrations of S. cerevisiae glycolysis [PDF]

open access: yes, 2008
The cell's cytoplasm is crowded by its various molecular components, resulting in a limited solvent capacity for the allocation of new proteins, thus constraining various cellular processes such as metabolism.
Barabási, AL   +3 more
core   +1 more source

Volatile Metabolites [PDF]

open access: yesMetabolites, 2011
Volatile organic compounds (volatiles) comprise a chemically diverse class of low molecular weight organic compounds having an appreciable vapor pressure under ambient conditions. Volatiles produced by plants attract pollinators and seed dispersers, and provide defense against pests and pathogens.
openaire   +3 more sources

Enantioselective Separation of Mirtazapine and Its Metabolites by Capillary Electrophoresis with Acetonitrile Field-Amplified Sample Stacking and Its Application

open access: yesMolecules, 2014
A simple, rapid and sensitive chiral capillary zone electrophoresis coupled with acetonitrile-field-amplified sample stacking method was developed that allows the simultaneous enantioselective separation of the mirtazapine, N-demethylmirtazapine, 8 ...
Jun Wen   +6 more
doaj   +1 more source

Using cell membrane chromatography and HPLC-TOF/MS method for in vivo study of active components from roots of Aconitum carmichaeli

open access: yesJournal of Pharmaceutical Analysis, 2011
An offline two-dimensional system combining a rat cardiac muscle cell membrane chromatography time-of-flight mass spectrometry (CMC-TOF/MS) with a high Performance liquid chromatography time-of-flight mass spectrometry (HPLC-TOF/MS) was established for ...
Yan Cao   +5 more
doaj   +1 more source

Quantifying Dynamic Regulation in Metabolic Pathways with Nonparametric Flux Inference [PDF]

open access: yes, 2019
One of the central tasks in systems biology is to understand how cells regulate their metabolism. Hierarchical regulation analysis is a powerful tool to study this regulation at the metabolic, gene-expression, and signaling levels.
He, Fei, Stumpf, Michael P H
core   +1 more source

Antimicrobial and Antioxidant Potential of Endophytic Fungi Isolated from Ethnomedicinal Plants of Western Ghats, Karnataka

open access: yesJournal of Pure and Applied Microbiology, 2017
A total of 79 endophytic fungal isolates were obtained from four wild medicinal plants-Tinospora cordifolia (Willd.) Hook.f and Thomson (Menispermaceae), Piper nigrum L., Piper longum L.
Fazilath Uzma , Srinivas Chowdappa
doaj   +1 more source

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