Results 231 to 240 of about 578,147 (248)

Genetic atlas of plasma metabolome across 40 human common diseases: mapping causal metabolites to disease risk. [PDF]

Genome Med
Li Y, Cai Y, Ma Q, Yang X, He C, Xu Y, Zhang M, Lu Z, Chen C, Ning C, Liu B, Wei Y, Li X, Jin M, Zhu X, Li B, Zhu Y, Huang C, Miao X, Tian J.   +19 more
europepmc   +1 more source

HPD is an m6A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m6A Methylating SLC7A11/GPX4

Advanced Science, EarlyView.
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang, Xintong Dai, Huanle Liu, Saiwei Hua, Hongkai Chang, Huanran Sun, Mingming Sun, Huifang Zhao, Kemin Ni, Fei Xie, Yaya Qiao, Qingle Gao, Chenxi Yu, Qijun Zhang, Jianshuang Guo, Chunze Zhang, Shuai Zhang, Changliang Shan   +17 more
wiley   +1 more source

Reproducibility of Metabolic Mapping Using 2D Multi-Slice Short-TE and GABA-Edited Spin-Echo MRSI at 3T in a Single Protocol. [PDF]

NMR Biomed
Zöllner HJ, Senapati DK, Özdemir İ, Chan KL, Oeltzschner G, Lin DDM, Barker PB.   +6 more
europepmc   +1 more source

ISOLATION, CHARACTERIZATION, AND NITRIC OXIDE PRODUCTION INHIBITORY ACTIVITIES OF THE METABOLITES FROM PSIDIUM GUAJAVA L.

H. H. T. Ngo, Tuan Anh Hoang Le, Cong Pham   +2 more
openalex   +1 more source

De Novo Gene Transcription of Connexin Mediates Cytoplasmic Fluid Exchange and Flocking Transitions in Physiological and Cancerous Epithelial Systems

Advanced Science, EarlyView.
EGF‐induced de novo transcription of connexins Cx26 and Cx31 promotes flocking behavior that fluidizes epithelia and enables coordinated collective migration. Connexin‐driven cytoplasmic exchange mechanistically links growth‐factor signaling to invasive dynamics.
Hind Abdo, Leonardo Barzaghi, Yuan Shen, Edoardo Bellini, Emanuele Martini, Serena Magni, Sara Barozzi, Fabrizio Orsenigo, Dario Parazzoli, Galina V. Beznoussenko, Jasmin Di Franco, Fabian Krautgasser, Jasmin Kaivola, Mario Cinquanta, Alessandro Lazzarin, Sara Sigismund, Johanna Ivaska, Roberto Cerbino, Giorgio Scita   +18 more
wiley   +1 more source

Comparative analysis of sLASER and PRESS techniques for magnetic resonance spectroscopy of the normal human brain. [PDF]

Sci Rep
Kim SK, Oh YA, Bae YJ, Cho SJ, Baik SH, Sunwoo L, Choi BS, Kim JH.   +7 more
europepmc   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

High-Resolution Brain Metabolic Imaging at Ultrahigh Field Using Extended Spatiospectral Encoding and Subspace Modeling. [PDF]

IEEE Trans Biomed Eng
Guo R, Li Y, Zhao Y, Jin W, Chai Y, Anderson A, Hassaneen W, Damon B, Wszalek T, Li Y, Wiesner HM, Zhu XH, Chen W, Sutton BP, Liang ZP.   +14 more
europepmc   +1 more source

Evidence of cancer: a systematic review of metabolomics in extracellular vesicles for cancer biomarker detection. [PDF]

Metabolomics
Mayhew M, Megram O, Roshan S, Smith MJ, White SJ, Wilson PB, Hunt JA, De Girolamo L, James V, Hunter E.   +9 more
europepmc   +1 more source

Plasma Metabolite Profiles of Children with Autism Spectrum Disorder. [PDF]

Metabolites
Mullin BH, Stuckey M, Brown SJ, Mullin S, Campbell PJ, Dudbridge F, Menni C, Walsh JP, Whitehouse AJO, Wilson SG.   +9 more
europepmc   +1 more source