The Intracellular Accumulation of Metabolites by Ram Spermatozoa During Incubation in the Presence of Exogenous Fructose [PDF]
RG Wales, EJ Humphries
openalex +1 more source
UnitedMet harnesses RNA-metabolite covariation to impute metabolite levels in clinical samples. [PDF]
Xie AX, Tansey W, Reznik E.
europepmc +1 more source
Colonic Submucosa Targeted Delivery of Probiotic and Rhein for Ulcerative Colitis Treatment
A novel orally drug‐probiotic co‐delivery system designated as Rh‐YBS for UC treatment, which highlights three innovations: (i) YPs involves colonic submucosa delivery via M cells; (ii) Rh (drug) promotes the colonization and growth of BS (probiotic) in the colon.
Lingqiang Li+21 more
wiley +1 more source
A Novel Approach for Comparing Selected Metabolites in Citrus Leaves and Fruits Across Datasets. [PDF]
Traband RC+16 more
europepmc +1 more source
Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao+12 more
wiley +1 more source
EFFECT OF LOWERED ESSENTIAL METABOLITES ON 8-AZAGUANINE INHIBITION
G. W. Kidder+2 more
openalex +1 more source
Metabolic Markers Demonstrate the Heterogeneity of Walking Ability in Non-Disabled Community-Dwelling Older Adults. [PDF]
Yao S+6 more
europepmc +1 more source
This study uses gut microbiome data to predict corticosteroid response in patients with immune thrombocytopenia (ITP). Fecal samples from 212 patients with ITP are sequenced. Six machine‐learning algorithms are used to train predictive models. The support vector machine‐based model integrated clinical data and selected microbial species, diversities ...
Feng‐Qi Liu+38 more
wiley +1 more source
A framework for predictive modeling of microbiome multi-omics data: latent interacting variable-effects (LIVE) modeling. [PDF]
Munoz Briones J, Brubaker DK.
europepmc +1 more source
Rational Design of Inner Ear Drug Delivery Systems
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu+5 more
wiley +1 more source