Results 21 to 30 of about 527,693 (324)
A total of 79 endophytic fungal isolates were obtained from four wild medicinal plants-Tinospora cordifolia (Willd.) Hook.f and Thomson (Menispermaceae), Piper nigrum L., Piper longum L.
Fazilath Uzma , Srinivas Chowdappa
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Farnesoid X receptor (FXR) and Takeda G-protein coupled receptor 5 (TGR5) are the two known bile acid (BA) sensitive receptors and are expressed in the intestine and liver as well as in extra-enterohepatic tissues.
Samuel A. J. Trammell+4 more
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Predicting pathways for old and new metabolites through clustering [PDF]
The diverse metabolic pathways are fundamental to all living organisms, as they harvest energy, synthesize biomass components, produce molecules to interact with the microenvironment, and neutralize toxins. While discovery of new metabolites and pathways continues, the prediction of pathways for new metabolites can be challenging.
arxiv
Endophytes are the mimicking the plant secondary metabolites as well as vast number chemical synthesizers inside plants and also have been extensively investigated for their endophytic microbial complement. Different parts of Rauwolfia tetraphylla L were
Ramesha Alurappa, Srinivas Chowdappa
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The advantage of leakage of essential metabolites and resultant symbiosis of diverse species [PDF]
Microbial communities display extreme diversity. A variety of strains or species coexist even when limited by a single resource. It has been argued that metabolite secretion creates new niches and facilitates such diversity. Nonetheless, it is still a controversial topic why cells secrete even essential metabolites so often; in fact, even under ...
arxiv +1 more source
Cardiometabolic disease affects the majority of individuals worldwide. The metabolite α-aminoadipic acid (2-AAA) was identified as a biomarker of Type 2 Diabetes (T2D). However, the mechanisms underlying this association remain unknown. DHTKD1, a central
Chuan Wang+2 more
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Sodium Danshensu (sodium d-(+)-β-(3,4-dihydroxyphenyl) lactate), one of the water-soluble ingredients in Salvia miltiorrhiza, exhibits potent relaxation of the coronary artery and anticoagulation effection.
Jingjing Jiang+6 more
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Astragali Radix (AR) is a clinically used herbal medicine with multiple immunomodulatory activities that can strengthen the activity and cytotoxicity of natural killer (NK) cells.
Xinyi Chai+10 more
doaj
Multidrug-resistant (MDR) Klebsiella pneumoniae is a top-prioritized Gram-negative pathogen with a high incidence in hospital-acquired infections. Polymyxins have resurged as a last-line therapy to combat Gram-negative “superbugs”, including MDR K ...
Wan Yean Chung+5 more
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Metabolite mediated modeling of microbial community dynamics captures emergent behavior more effectively than species-species modeling [PDF]
Personalized models of the gut microbiome are valuable for disease prevention and treatment. For this, one requires a mathematical model that predicts microbial community composition and the emergent behavior of microbial communities. We seek a modeling strategy that can capture emergent behavior when built from sets of universal individual ...
arxiv +1 more source