Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji +7 more
wiley +1 more source
Digestible and metabolizable energy in soybean meal and soybean hulls when fed to growing pigs or sows. [PDF]
Kim Y, Lee SA, Stein HH.
europepmc +1 more source
Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source
Accuracy of Predictive Equations for Metabolizable Energy Compared to Energy Content of Foods for Dogs and Cats Estimated by In Vivo Methods in Brazil. [PDF]
Marchi PH +11 more
europepmc +1 more source
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales +11 more
wiley +1 more source
In vitro studies for the prediction of digestibility, metabolisable energy content and protein fermentability of shrubs and tree fodders [PDF]
Arbelot, Brigitte, Steingass, H.
core
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement +12 more
wiley +1 more source
Assessment of apparent metabolizable energy, and ileal amino acid digestibility of full-fat black soldier fly larvae (Hermetia illucens) in broiler chickens. [PDF]
Alafif MS +6 more
europepmc +1 more source
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim +6 more
wiley +1 more source
Steady state changes in mitochondrial electrical potential and proton gradient in perfused liver from rats fed a high fat diet. [PDF]
IOSSA, SUSANNA +3 more
core +1 more source

