Results 231 to 240 of about 173,467 (269)
Some of the next articles are maybe not open access.
2022
The purpose of this manuscript will be to convince the reader to dive deeper into NMR spectroscopy and prevent the technique from being just another "black-box" in the lab. We will try to concisely highlight interesting topics and supply additional references for further exploration at each stage.
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The purpose of this manuscript will be to convince the reader to dive deeper into NMR spectroscopy and prevent the technique from being just another "black-box" in the lab. We will try to concisely highlight interesting topics and supply additional references for further exploration at each stage.
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Current Protocols in Molecular Biology, 2010
AbstractAlong with genes and proteins, metabolites play important roles in sustaining life. Their functions include “primary” functions in metabolism and energy storage, as well as “secondary” functions in cell‐to‐cell signaling, metal acquisition, and virulence. There remains much to be learned about the in vivo roles of metabolites.
Nawaporn, Vinayavekhin +1 more
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AbstractAlong with genes and proteins, metabolites play important roles in sustaining life. Their functions include “primary” functions in metabolism and energy storage, as well as “secondary” functions in cell‐to‐cell signaling, metal acquisition, and virulence. There remains much to be learned about the in vivo roles of metabolites.
Nawaporn, Vinayavekhin +1 more
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2019
The human metabolome is the cumulative product of ingested metabolites and those produced by the body and its microbiota. Together these metabolites can dynamically report on the health and disease state of an individual, as well as their response to drug treatments and other external perturbations.
David P, Marciano, Michael P, Snyder
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The human metabolome is the cumulative product of ingested metabolites and those produced by the body and its microbiota. Together these metabolites can dynamically report on the health and disease state of an individual, as well as their response to drug treatments and other external perturbations.
David P, Marciano, Michael P, Snyder
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2014
Metabolites, the chemical entities that are transformed during metabolism, provide a functional readout of cellular biochemistry that offers the best prediction of the phenotype and the nature of a disease. Mass spectrometry now allows thousands of metabolites to be quantitated.
Francis G, Bowling, Mervyn, Thomas
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Metabolites, the chemical entities that are transformed during metabolism, provide a functional readout of cellular biochemistry that offers the best prediction of the phenotype and the nature of a disease. Mass spectrometry now allows thousands of metabolites to be quantitated.
Francis G, Bowling, Mervyn, Thomas
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Journal of Hypertension, 2014
Hypertension is the most prevalent chronic medical condition and a major risk factor for cardiovascular morbidity and mortality. In the majority of hypertensive cases, the underlying cause of hypertension cannot be easily identified because of the heterogeneous, polygenic and multi-factorial nature of hypertension.
Nikolic, Sonja B. +3 more
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Hypertension is the most prevalent chronic medical condition and a major risk factor for cardiovascular morbidity and mortality. In the majority of hypertensive cases, the underlying cause of hypertension cannot be easily identified because of the heterogeneous, polygenic and multi-factorial nature of hypertension.
Nikolic, Sonja B. +3 more
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2021
Metabolic reprogramming is an important characteristics of glioma, the most common form of malignant brain tumor. In this chapter, we aim to discuss some of the recently discovered metabolic alterations in glioma, including the dysregulated TCA cycle, amino acid, nucleotide, and lipid metabolism.
Sizhe, Feng, Yutong, Liu
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Metabolic reprogramming is an important characteristics of glioma, the most common form of malignant brain tumor. In this chapter, we aim to discuss some of the recently discovered metabolic alterations in glioma, including the dysregulated TCA cycle, amino acid, nucleotide, and lipid metabolism.
Sizhe, Feng, Yutong, Liu
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Clinica Chimica Acta, 2012
Metabolomics is a powerful technique for the discovery of novel biomarkers and elucidation of biochemical pathways to improve diagnosis, prognosis and therapy. An advantage of this approach is its ability to assess global metabolic profiles to enhance pathologic characterization.
Aihua, Zhang +3 more
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Metabolomics is a powerful technique for the discovery of novel biomarkers and elucidation of biochemical pathways to improve diagnosis, prognosis and therapy. An advantage of this approach is its ability to assess global metabolic profiles to enhance pathologic characterization.
Aihua, Zhang +3 more
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Understanding the metabolome – challenges for metabolomics
Nutrition Bulletin, 2008SummaryMetabolomics is a comprehensive method for metabolite assessment, measuring the overall metabolic signature of biological samples. This approach opens up many possibilities in areas such as new biomarker discovery and hypothesis generation. The application of metabolomics is growing rapidly but many challenges must first be addressed before it ...
M. C. Walsh +3 more
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2009
Metabolomics, one of the "omic" sciences in systems biology, is the global assessment and validation of endogenous small-molecule biochemicals (metabolites) within a biologic system. Initially, putative quantitative metabolic biomarkers for cancer detection and/or assessment of efficacy of anticancer treatment are usually discovered in a preclinical ...
Natalie J, Serkova, Kristine, Glunde
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Metabolomics, one of the "omic" sciences in systems biology, is the global assessment and validation of endogenous small-molecule biochemicals (metabolites) within a biologic system. Initially, putative quantitative metabolic biomarkers for cancer detection and/or assessment of efficacy of anticancer treatment are usually discovered in a preclinical ...
Natalie J, Serkova, Kristine, Glunde
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