Results 61 to 70 of about 422,605 (335)

Extraction for Metabolomics: Access to The Metabolome

Phytochemical Analysis, 2014
ABSTRACTIntroductionThe value of information obtained from a metabolomic study depends on how much of the metabolome is present in analysed samples. Thus, only a comprehensive and reproducible extraction method will provide reliable data because the metabolites that will be measured are those that were extracted and all conclusions will be built around
Mushtaq, M.Y., Choi, Y.H., Verpoorte, R., Wilson, E.G.   +3 more
openaire   +3 more sources

mzMatch-ISO: an R tool for the annotation and relative quantification of isotope-labelled mass spectrometry data [PDF]

, 2013
<p>Motivation: Stable isotope-labelling experiments have recently gained increasing popularity in metabolomics studies, providing unique insights into the dynamics of metabolic fluxes, beyond the steady-state information gathered by routine mass ...
Achuthanunni Chokkathukalam, Andris Jankevics, Breitling, Bueschl, Chaneton, Creek, Darren J. Creek, Dunn, Fiona Achcar, Gipson, Jankevics, Kanehisa, Le, Melamud, Michael P. Barrett, Rainer Breitling, Rogers, Scheltema, Smith, t’Kindt, Weber, Wishart   +21 more
core   +5 more sources

MetaboAnalystR 4.0: a unified LC-MS workflow for global metabolomics

Nature Communications
The wide applications of liquid chromatography - mass spectrometry (LC-MS) in untargeted metabolomics demand an easy-to-use, comprehensive computational workflow to support efficient and reproducible data analysis.
Zhiqiang Pang, Lei Xu, Charles Viau, Yao Lu, Reza Salavati, Niladri Basu, Jianguo Xia   +6 more
semanticscholar   +1 more source

¹³C NMR metabolomics: applications at natural abundance. [PDF]

, 2014
(13)C NMR has many advantages for a metabolomics study, including a large spectral dispersion, narrow singlets at natural abundance, and a direct measure of the backbone structures of metabolites.
Clendinen, Chaevien, Edison, Arthur, Hahn, Daniel, Lee-McMullen, Brittany, Stupp, Gregory, Vandenborne, Krista, Walter, Glenn, Williams, Caroline   +7 more
core   +3 more sources

New software tools, databases, and resources in metabolomics: updates from 2020

Metabolomics, 2021
Precision medicine, space exploration, drug discovery to characterization of dark chemical space of habitats and organisms, metabolomics takes a centre stage in providing answers to diverse biological, biomedical, and environmental questions.
B. Misra
semanticscholar   +1 more source

Suspect screening analysis to improve untargeted and targeted UHPLC-qToF approaches: the biodegradability of a proton pump inhibitor medicine and a natural medical device

Scientific Reports
Suspect screening and untargeted analysis using UHPLC-qToF are two advanced analytical approaches now used to achieve an extensive chemical profile of samples, which are then typically confirmed through targeted analysis.
Luisa Mattoli, Giacomo Proietti, Giada Fodaroni, Claudio Marzio Quintiero, Michela Burico, Mattia Gianni, Emiliano Giovagnoni, Valentino Mercati, Claudio Santi   +8 more
doaj   +1 more source

MetaboCraft: building a Minecraft plugin for metabolomics [PDF]

, 2018
Motivation: The rapid advances in metabolomics pose a significant challenge in presentation and interpretation of results. Development of new, engaging visual aids is crucial to advancing our understanding of new findings. Results: We have developed
Burgess, Karl, Daly, Rónán, Megalios, Anargyros   +2 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Ametryn removal by Metarhizium brunneum: Biodegradation pathway proposal and metabolic background revealed [PDF]

, 2018
Ametryn is a representative of a class of s-triazine herbicides absorbed by plant roots and leaves and characterized as a photosynthesis inhibitor. It is still in use in some countries in the farming of pineapples, soybean, corn, cotton, sugar cane or ...
Abigail, Allan, Anna Kuśmierska, Bernat, Bernat, Borges, Chen, Chen, Chirnside, Długoński, Elbashir, Fang, Fujii, Gao, Govantes, Grillo, Hayes, Ji, Krishnan, Lee, Liang, Liu, Liu, Lobos, Ma, Navaratna, Noguchi, Payá, Pereira, Peters, Prosen, Przemysław Bernat, QuEChERS, Rafał Szewczyk, Rocha, Różalska, Sandoval-Carrasco, Scialli, Shah, Signorelli, Soboń, Solomon, Stoker, Szewczyk, Szewczyk, Tejada, Tripathi, Velisek, World Health Organization   +48 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source