Results 41 to 50 of about 422,605 (335)
Nanomaterials, 2022 Gold nanoparticles (GNPs) have shown great potential in diagnostic and therapeutic applications in diseases, such as cancer. Despite GNP versatility, there is conflicting data regarding the toxicity of their overall functionalization chemistry for ...
Danielle Mulder +3 more
doaj +1 more source
Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis. [PDF]
, 2014 ImportanceWhile "omics" studies have advanced our understanding of inflammatory skin diseases, metabolomics is mostly an unexplored field in dermatology.ObjectiveWe sought to elucidate the pathogenesis of psoriatic diseases by determining the differences
Armstrong, April W +6 more
core +2 more sources
The Potential of Metabolomics in Biomedical Applications
Metabolites, 2022 The metabolome offers a dynamic, comprehensive, and precise picture of the phenotype. Current high-throughput technologies have allowed the discovery of relevant metabolites that characterize a wide variety of human phenotypes with respect to health ...
V. González-Covarrubias +2 more
semanticscholar +1 more source
The METLIN small molecule dataset for machine learning-based retention time prediction
Nature Communications, 2019 The use of machine learning for identifying small molecules through their retention time’s predictions has been challenging so far. Here the authors combine a large database of liquid chromatography retention time with a deep learning approach to enable ...
Xavier Domingo-Almenara +8 more
doaj +1 more source
Current Genomics, 2011 Microbial metabolomics constitutes an integrated component of systems biology. By studying the complete set of metabolites within a microorganism and monitoring the global outcome of interactions between its development processes and the environment, metabolomics can potentially provide a more accurate snap shot of the actual physiological state of the
openaire +2 more sources
NMR and Metabolomics—A Roadmap for the Future
Metabolites, 2022 Metabolomics investigates global metabolic alterations associated with chemical, biological, physiological, or pathological processes. These metabolic changes are measured with various analytical platforms including liquid chromatography-mass ...
D. Wishart +11 more
semanticscholar +1 more source
SECIMTools: a suite of metabolomics data analysis tools
BMC Bioinformatics, 2018 Background Metabolomics has the promise to transform the area of personalized medicine with the rapid development of high throughput technology for untargeted analysis of metabolites.
Alexander S. Kirpich +8 more
doaj +1 more source
Bile acids regulate MAdCAM-1 expression to link the gut microbiota to cancer immunosurveillance
OncoImmunology, 2023 In a recent paper in Science, Fidelle et al. unravel a gut immune checkpoint that is subverted by antibiotic treatment. Post-antibiotic dysbiosis of the ileum causes an increase in bile acids that downregulate MAdCAM−1, thereby triggering the exodus of ...
Marine Fidelle +3 more
doaj +1 more source
Applying metabolomics to cardiometabolic intervention studies and trials: past experiences and a roadmap for the future [PDF]
, 2016 Metabolomics and lipidomics are emerging methods for detailed phenotyping of small molecules in samples. It is hoped that such data will: (i) enhance baseline prediction of patient response to pharmacotherapies (beneficial or adverse); (ii) reveal ...
Preiss, David +3 more
core +2 more sources
BMC Plant Biology, 2021 Background Surveillance of potential pathogens is a key feature of plant innate immunity. For non-self-recognition plants rely on the perception of pathogen-derived molecules.
Dylan R. Zeiss +3 more
doaj +1 more source