Results 31 to 40 of about 422,605 (335)

PLS2 in Metabolomics [PDF]

open access: yesMetabolites, 2019
Metabolomics is the systematic study of the small-molecule profiles of biological samples produced by specific cellular processes. The high-throughput technologies used in metabolomic investigations generate datasets where variables are strongly correlated and redundancy is present in the data.
Matteo Stocchero   +5 more
openaire   +4 more sources

Differences in the Stool Metabolome between Vegans and Omnivores: Analyzing the NIST Stool Reference Material

open access: yesMetabolites, 2023
To gain confidence in results of omic-data acquisitions, methods must be benchmarked using validated quality control materials. We report data combining both untargeted and targeted metabolomics assays for the analysis of four new human fecal reference ...
Raquel Cumeras   +5 more
doaj   +1 more source

Metabolomics

open access: yesCurrent Drug Metabolism, 2008
Metabolomics is based on the simultaneous analysis of multiple low-molecular-weight metabolites from a given sample. The goals of metabolomics are to catalog and quantify the myriad small molecules found in biological fluids under different conditions. The metabolomics represents the collection of all metabolites in a biological organism, and metabolic
V S, Gomase   +3 more
openaire   +4 more sources

Intracellular metabolites in marine microorganisms during an experiment evaluating microbial mortality [PDF]

open access: yes, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Longnecker, K., & Kujawinski, E. B.
Kujawinski, Elizabeth B.   +1 more
core   +1 more source

Xenobiotic Metabolomics: Major Impact on the Metabolome [PDF]

open access: yesAnnual Review of Pharmacology and Toxicology, 2012
Xenobiotics are encountered by humans on a daily basis and include drugs, environmental pollutants, cosmetics, and even components of the diet. These chemicals undergo metabolism and detoxication to produce numerous metabolites, some of which have the potential to cause unintended effects such as toxicity.
Caroline H, Johnson   +3 more
openaire   +2 more sources

Differentiating signals to make biological sense – a guide through databases for MS-based non-targeted metabolomics [PDF]

open access: yes, 2017
Metabolite identification is one of the most challenging steps in metabolomics studies and reflects one of the greatest bottlenecks in the entire workflow.
Armitage, Emily Grace   +4 more
core   +1 more source

Cancer Metabolomics and the Human Metabolome Database [PDF]

open access: yesMetabolites, 2016
The application of metabolomics towards cancer research has led to a renewed appreciation of metabolism in cancer development and progression. It has also led to the discovery of metabolite cancer biomarkers and the identification of a number of novel cancer causing metabolites.
David S. Wishart   +3 more
openaire   +3 more sources

MetaboAnalyst 3.0—making metabolomics more meaningful

open access: yesNucleic Acids Res., 2015
MetaboAnalyst (www.metaboanalyst.ca) is a web server designed to permit comprehensive metabolomic data analysis, visualization and interpretation. It supports a wide range of complex statistical calculations and high quality graphical rendering functions
J. Xia   +3 more
semanticscholar   +1 more source

Metabolomics-centered mining of plant metabolic diversity and function: past decade and future perspectives.

open access: yesMolecular Plant, 2022
Plants are natural experts in organic synthesis being able to generate large numbers of specific metabolites with widely varying structures in order to adapt to variable survival challenges.
S. Shen   +4 more
semanticscholar   +1 more source

Highly sensitive CE-ESI-MS analysis of N-glycans from complex biological samples

open access: yesNature Communications, 2019
In-depth characterization of complex glycomes is complicated by the immense structural diversity of glycans. Here, the authors present a mass spectrometry-based strategy for untargeted, sensitive glycan profiling and identify 167 N-glycan compositions in
Guinevere S. M. Lageveen-Kammeijer   +7 more
doaj   +1 more source

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