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Metabolomics is the systematic study of the small-molecule profiles of biological samples produced by specific cellular processes. The high-throughput technologies used in metabolomic investigations generate datasets where variables are strongly correlated and redundancy is present in the data.
Matteo Stocchero +5 more
openaire +4 more sources
To gain confidence in results of omic-data acquisitions, methods must be benchmarked using validated quality control materials. We report data combining both untargeted and targeted metabolomics assays for the analysis of four new human fecal reference ...
Raquel Cumeras +5 more
doaj +1 more source
Metabolomics is based on the simultaneous analysis of multiple low-molecular-weight metabolites from a given sample. The goals of metabolomics are to catalog and quantify the myriad small molecules found in biological fluids under different conditions. The metabolomics represents the collection of all metabolites in a biological organism, and metabolic
V S, Gomase +3 more
openaire +4 more sources
Intracellular metabolites in marine microorganisms during an experiment evaluating microbial mortality [PDF]
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Longnecker, K., & Kujawinski, E. B.
Kujawinski, Elizabeth B. +1 more
core +1 more source
Xenobiotic Metabolomics: Major Impact on the Metabolome [PDF]
Xenobiotics are encountered by humans on a daily basis and include drugs, environmental pollutants, cosmetics, and even components of the diet. These chemicals undergo metabolism and detoxication to produce numerous metabolites, some of which have the potential to cause unintended effects such as toxicity.
Caroline H, Johnson +3 more
openaire +2 more sources
Differentiating signals to make biological sense – a guide through databases for MS-based non-targeted metabolomics [PDF]
Metabolite identification is one of the most challenging steps in metabolomics studies and reflects one of the greatest bottlenecks in the entire workflow.
Armitage, Emily Grace +4 more
core +1 more source
Cancer Metabolomics and the Human Metabolome Database [PDF]
The application of metabolomics towards cancer research has led to a renewed appreciation of metabolism in cancer development and progression. It has also led to the discovery of metabolite cancer biomarkers and the identification of a number of novel cancer causing metabolites.
David S. Wishart +3 more
openaire +3 more sources
MetaboAnalyst 3.0—making metabolomics more meaningful
MetaboAnalyst (www.metaboanalyst.ca) is a web server designed to permit comprehensive metabolomic data analysis, visualization and interpretation. It supports a wide range of complex statistical calculations and high quality graphical rendering functions
J. Xia +3 more
semanticscholar +1 more source
Plants are natural experts in organic synthesis being able to generate large numbers of specific metabolites with widely varying structures in order to adapt to variable survival challenges.
S. Shen +4 more
semanticscholar +1 more source
Highly sensitive CE-ESI-MS analysis of N-glycans from complex biological samples
In-depth characterization of complex glycomes is complicated by the immense structural diversity of glycans. Here, the authors present a mass spectrometry-based strategy for untargeted, sensitive glycan profiling and identify 167 N-glycan compositions in
Guinevere S. M. Lageveen-Kammeijer +7 more
doaj +1 more source

