Results 31 to 40 of about 173,467 (269)

Metabolomics in Otorhinolaryngology

Frontiers in Molecular Biosciences, 2022
Otorhinolaryngology (Ear, Nose and Throat-ENT) focuses on inflammatory, immunological, infectious, and neoplastic disorders of the head and neck and on their medical and surgical therapy. The fields of interest of this discipline are the ear, the nose and its paranasal sinuses, the oral cavity, the pharynx, the larynx, and the neck.
Noto, Antonio, Piras, Cristina, Atzori, Luigi, Mussap, Michele, Albera, Andrea, Albera, Roberto, Casani, Augusto Pietro, Capobianco, Silvia, Fanos, Vassilios   +8 more
openaire   +5 more sources

Metabolomics and Atherosclerosis [PDF]

Current Atherosclerosis Reports, 2010
Metabolites reflect the dynamic processes underlying cellular homeostasis. Recent advances in analytical chemistry and molecular biology have set the stage for metabolite profiling to help us understand complex molecular processes and physiology. Metabolomics is the comparative analysis of metabolite flux and how it relates to biological phenotypes. As
Sascha N, Goonewardena, Lisa E, Prevette, Ankit A, Desai   +2 more
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Cell Metabolomics [PDF]

OMICS: A Journal of Integrative Biology, 2013
Abstract Metabolomics technologies enable the examination and identification of endogenous biochemical reaction products, revealing information on the precise metabolic pathways and processes within a living cell. Metabolism is either directly or indirectly involved with every aspect of cell function, and metabolomics is thus believed
Aihua, Zhang, Hui, Sun, Hongying, Xu, Shi, Qiu, Xijun, Wang   +4 more
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Microbiome and Metabolomics

Medical Journal of Babylon, 2023
The relationship between microbiome and metabolomics by studying the microbiota living in the human body and studying their effects on the concentration of metabolites, also to study effects of microbiota colonization on other bacteria or living organism entering the body.
Noor S K Al-Khafaji, Hussein O M Al-Dahmoshi, Zainab Adil Ghani Chabuck, Zena Abdul-Ameer Mahdi, Muhammad Akram, Adrish Sohail, Umme Laila, Rida Zainab, Muhammad Talha Khalil, Momina Iftikhar, Fethi Ahmet Ozdemir   +10 more
openaire   +2 more sources

Metabolomics for the masses: The future of metabolomics in a personalized world

European Journal of Molecular & Clinical Medicine, 2017
Current clinical practices focus on a small number of biochemical directly related to the pathophysiology with patients and thus only describe a very limited metabolome of a patient and fail to consider the interations of these small molecules.
Trivedi, Drupad; id_orcid 0000-0001-7969-0195, Hollywood, Katherine; id_orcid 0000-0002-7028-047X, Goodacre, Royston   +2 more
openaire   +4 more sources

Suspect screening analysis to improve untargeted and targeted UHPLC-qToF approaches: the biodegradability of a proton pump inhibitor medicine and a natural medical device

Scientific Reports
Suspect screening and untargeted analysis using UHPLC-qToF are two advanced analytical approaches now used to achieve an extensive chemical profile of samples, which are then typically confirmed through targeted analysis.
Luisa Mattoli, Giacomo Proietti, Giada Fodaroni, Claudio Marzio Quintiero, Michela Burico, Mattia Gianni, Emiliano Giovagnoni, Valentino Mercati, Claudio Santi   +8 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Metabolomics: A Primer [PDF]

Trends in Biochemical Sciences, 2017
Metabolomics generates a profile of small molecules that are derived from cellular metabolism and can directly reflect the outcome of complex networks of biochemical reactions, thus providing insights into multiple aspects of cellular physiology. Technological advances have enabled rapid and increasingly expansive data acquisition with samples as small
Xiaojing Liu, Jason W. Locasale
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Elemental metabolomics [PDF]

Briefings in Bioinformatics, 2017
Elemental metabolomics is quantification and characterization of total concentration of chemical elements in biological samples and monitoring of their changes. Recent advances in inductively coupled plasma mass spectrometry have enabled simultaneous measurement of concentrations of > 70 elements in biological samples.
Ping Zhang 0008, Constantinos A. Georgiou, Vladimir Brusic   +2 more
openaire   +3 more sources