Results 11 to 20 of about 422,605 (335)
Software Tools and Approaches for Compound Identification of LC-MS/MS Data in Metabolomics. [PDF]
Metabolites, 2018 The annotation of small molecules remains a major challenge in untargeted mass spectrometry-based metabolomics. We here critically discuss structured elucidation approaches and software that are designed to help during the annotation of unknown compounds.
Blaženović, Ivana +3 more
core +4 more sources
Cell Metabolism, 2007 Metabolomics is the systematic identification and quantitation of all metabolites in a given organism or biological sample. The enhanced resolution provided by nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS), along with powerful chemometric software, allows the simultaneous determination and comparison of thousands of chemical ...
Idle, Jeffrey R., Gonzalez, Frank J.
+6 more sources
MetaboLights: open data repository for metabolomics
Nucleic Acids Research, 2023 MetaboLights is a global database for metabolomics studies including the raw experimental data and the associated metadata. The database is cross-species and cross-technique and covers metabolite structures and their reference spectra as well as their ...
Ozgur Yurekten +6 more
semanticscholar +1 more source
Cardiovascular Metabolomics [PDF]
Circulation Research, 2018 Disturbances in cardiac metabolism underlie most cardiovascular diseases. Metabolomics, one of the newer omics technologies, has emerged as a powerful tool for defining changes in both global and cardiac-specific metabolism that occur across a spectrum of cardiovascular disease states.
Robert W, McGarrah +4 more
openaire +2 more sources
Aspergillus Metabolome Database for Mass Spectrometry Metabolomics [PDF]
Journal of Fungi, 2021 The Aspergillus Metabolome Database is a free online resource to perform metabolite annotation in mass spectrometry studies devoted to the genus Aspergillus. The database was created by retrieving and curating information on 2811 compounds present in 601 different species and subspecies of the genus Aspergillus.
Alberto Gil-de-la-Fuente +7 more
openaire +3 more sources
OMICS: A Journal of Integrative Biology, 2013 Abstract Metabolomics technologies enable the examination and identification of endogenous biochemical reaction products, revealing information on the precise metabolic pathways and processes within a living cell. Metabolism is either directly or indirectly involved with every aspect of cell function, and metabolomics is thus believed
Aihua, Zhang +4 more
openaire +2 more sources
Briefings in Bioinformatics, 2017 Elemental metabolomics is quantification and characterization of total concentration of chemical elements in biological samples and monitoring of their changes. Recent advances in inductively coupled plasma mass spectrometry have enabled simultaneous measurement of concentrations of > 70 elements in biological samples.
Zhang, Ping +2 more
openaire +3 more sources
Current Protocols in Molecular Biology, 2012 AbstractThe metabolome is the terminal downstream product of the genome and consists of the total complement of all the low‐molecular‐weight molecules (metabolites) in a cell, tissue, or organism. Metabolomics aims to measure a wide breadth of small molecules in the context of physiological stimuli or disease states.
Lee D, Roberts +3 more
openaire +2 more sources
Pretreating and normalizing metabolomics data for statistical analysis
Genes and Diseases, 2023 Metabolomics as a research field and a set of techniques is to study the entire small molecules in biological samples. Metabolomics is emerging as a powerful tool generally for precision medicine.
Jun Sun, Yinglin Xia
semanticscholar +1 more source
MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis
Nucleic Acids Res., 2018 We present a new update to MetaboAnalyst (version 4.0) for comprehensive metabolomic data analysis, interpretation, and integration with other omics data.
Jasmine Chong +7 more
semanticscholar +1 more source