Results 21 to 30 of about 173,467 (269)
Computational Metabolomics: A Framework for the Million Metabolome [PDF]
Chemical Research in Toxicology, 2016 "Sola dosis facit venenum." These words of Paracelsus, "the dose makes the poison", can lead to a cavalier attitude concerning potential toxicities of the vast array of low abundance environmental chemicals to which humans are exposed. Exposome research teaches that 80-85% of human disease is linked to environmental exposures.
Karan, Uppal +5 more
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Microbiology Spectrum, 2022 The highly adaptive cellular response of Mycobacterium tuberculosis to various antibiotics and the high costs for clinical trials, hampers the development of novel antimicrobial agents with improved efficacy and safety.
Kirsten E. Knoll +2 more
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Cardiovascular Metabolomics [PDF]
Circulation Research, 2018 Disturbances in cardiac metabolism underlie most cardiovascular diseases. Metabolomics, one of the newer omics technologies, has emerged as a powerful tool for defining changes in both global and cardiac-specific metabolism that occur across a spectrum of cardiovascular disease states.
Robert W, McGarrah +4 more
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BMC Plant Biology, 2023 Background Puccinia striiformis f. sp. tritici (Pst) is an economically devasting disease that is prominent in cereal crops such as wheat (Triticum aestivum). The fungal pathogen can cause approximately 30–70% losses in crop productivity and yields.
Manamele Dannies Mashabela +5 more
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Scientific Reports, 2022 The AbsoluteIDQ p400 HR kit is a commercial product for targeted metabolomics. While the kit has been validated for human plasma and serum, adherent cell lysates have not yet been evaluated.
Raphaela Fritsche-Guenther +3 more
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Serum-Urine Matched Metabolomics for Predicting Progression of Henoch-Schonlein Purpura Nephritis
Frontiers in Medicine, 2021 Henoch-Schonlein purpura nephritis (HSPN) is a common glomerulonephritis secondary to Henoch-Schonlein purpura (HSP) that affects systemic metabolism. Currently, there is a rarity of biomarkers to predict the progression of HSPN.
Qian Zhang +7 more
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Extraction for Metabolomics: Access to The Metabolome
Phytochemical Analysis, 2014 ABSTRACTIntroductionThe value of information obtained from a metabolomic study depends on how much of the metabolome is present in analysed samples. Thus, only a comprehensive and reproducible extraction method will provide reliable data because the metabolites that will be measured are those that were extracted and all conclusions will be built around
Mushtaq, M.Y. +3 more
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Cold Spring Harbor Protocols, 2017 Budding yeast has from the beginning been a major eukaryotic model for the study of metabolic network structure and function. This is attributable to both its genetic and biochemical capacities and its role as a workhorse in food production and biotechnology.
Amy A, Caudy +2 more
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Plasma acylcarnitine in elderly Taiwanese: as biomarkers of possible sarcopenia and sarcopenia
BMC Geriatrics, 2023 Background Sarcopenia is defined as the disease of muscle loss and dysfunction. The prevalence of sarcopenia is strongly age-dependent. It could bring about disability, hospitalization, and mortality.
Chi-Jen Lo +6 more
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Metabolomics of a Superorganism [PDF]
The Journal of Nutrition, 2007 The human can be thought of as a human-microbe hybrid, and the health of this superorganism will be affected by intrinsic properties such as human genetics, diurnal cycles, and age and by extrinsic factors such as lifestyle choices (food and drink, drug intake) and the acquisition of a stable "healthy" gut microflora (the so-called microbiome ...
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