Results 21 to 30 of about 186,058 (269)
Metabolites, 2023 To gain confidence in results of omic-data acquisitions, methods must be benchmarked using validated quality control materials. We report data combining both untargeted and targeted metabolomics assays for the analysis of four new human fecal reference ...
Raquel Cumeras +5 more
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Metabolomics of a Superorganism [PDF]
The Journal of Nutrition, 2007 The human can be thought of as a human-microbe hybrid, and the health of this superorganism will be affected by intrinsic properties such as human genetics, diurnal cycles, and age and by extrinsic factors such as lifestyle choices (food and drink, drug intake) and the acquisition of a stable "healthy" gut microflora (the so-called microbiome ...
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Metabolomics and Atherosclerosis [PDF]
Current Atherosclerosis Reports, 2010 Metabolites reflect the dynamic processes underlying cellular homeostasis. Recent advances in analytical chemistry and molecular biology have set the stage for metabolite profiling to help us understand complex molecular processes and physiology. Metabolomics is the comparative analysis of metabolite flux and how it relates to biological phenotypes. As
Sascha N, Goonewardena +2 more
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The METLIN small molecule dataset for machine learning-based retention time prediction
Nature Communications, 2019 The use of machine learning for identifying small molecules through their retention time’s predictions has been challenging so far. Here the authors combine a large database of liquid chromatography retention time with a deep learning approach to enable ...
Xavier Domingo-Almenara +8 more
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Highly sensitive CE-ESI-MS analysis of N-glycans from complex biological samples
Nature Communications, 2019 In-depth characterization of complex glycomes is complicated by the immense structural diversity of glycans. Here, the authors present a mass spectrometry-based strategy for untargeted, sensitive glycan profiling and identify 167 N-glycan compositions in
Guinevere S. M. Lageveen-Kammeijer +7 more
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Nanomaterials, 2022 Gold nanoparticles (GNPs) have shown great potential in diagnostic and therapeutic applications in diseases, such as cancer. Despite GNP versatility, there is conflicting data regarding the toxicity of their overall functionalization chemistry for ...
Danielle Mulder +3 more
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Bile acids regulate MAdCAM-1 expression to link the gut microbiota to cancer immunosurveillance
OncoImmunology, 2023 In a recent paper in Science, Fidelle et al. unravel a gut immune checkpoint that is subverted by antibiotic treatment. Post-antibiotic dysbiosis of the ileum causes an increase in bile acids that downregulate MAdCAM−1, thereby triggering the exodus of ...
Marine Fidelle +3 more
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SECIMTools: a suite of metabolomics data analysis tools
BMC Bioinformatics, 2018 Background Metabolomics has the promise to transform the area of personalized medicine with the rapid development of high throughput technology for untargeted analysis of metabolites.
Alexander S. Kirpich +8 more
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Scientific Reports, 2017 Sialylation is a glycosylation feature that occurs in different linkages at the non-reducing end of a glycan moiety, the linkage isomers are often differentially associated with various biological processes.
Guinevere S. M. Kammeijer +7 more
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BMC Plant Biology, 2021 Background Surveillance of potential pathogens is a key feature of plant innate immunity. For non-self-recognition plants rely on the perception of pathogen-derived molecules.
Dylan R. Zeiss +3 more
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