Results 221 to 230 of about 55,850 (272)

Biased allosteric agonism and modulation of metabotropic glutamate receptor 5: Implications for optimizing preclinical neuroscience drug discovery

, 2016
Kathy Sengmany, Junaid Singh, Gregory D. Stewart, P. Jeffrey Conn, Arthur Christopoulos, Karen J. Gregory   +5 more
openalex   +1 more source

Recovery of Decreased Metabotropic Glutamate Receptor 5 Availability in Abstinent Alcohol-Dependent Patients. [PDF]

J Nucl Med, 2020
Ceccarini J, Leurquin-Sterk G, Crunelle CL, de Laat B, Bormans G, Peuskens H, Van Laere K.   +6 more
europepmc   +1 more source

Investigating the pharmacology, dimerisation and receptor-dependent toxicology of metabotropic glutamate receptor 5

, 2017
Andrew Daniel Weaver
openalex   +1 more source

Discovery of novel positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)

, 2011
Jeffrey Varnes, Andrew P. Marcus, Russell C. Mauger, Scott Throner, Valerie Hoesch, Megan M. King, Xia Wang, Linda A. Sygowski, Nathan Spear, R.A. Gadient, Dean G. Brown, James B. Campbell   +11 more
openalex   +1 more source

Development of [18F]-PSS223 as a PET Tracer for Imaging of Metabotropic Glutamate Receptor Subtype 5 (mGluR5)

, 2012
Selena Milicevic Sephton, Patrick Dennler, Dominique S. Leutwiler, Linjing Mu, Roger Schibli, Stefanie D. Krämer, Simon M. Ametamey   +6 more
openalex   +2 more sources

Metabotropic glutamate receptor 5 signaling and appetitive Pavlovian behavior: implications for the treatment of addiction. [PDF]

Neuropsychopharmacology, 2019
Richard JM.
europepmc   +1 more source

Discovery of 7-(Pyridin-3-yl)thieno[3,2- b ]pyridine-5-carboxamides as Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5

Scott H. Henderson, Anna E. Ringuette, David Whomble, Rory A. Capstick, Alexa E. Richardson, Mallory A. Maurer, Natasha B. Billard, Xia Lei, Joshua C. Wilkinson, Sri H. Kethanapalli, Hyekyung P. Cho, Alice L. Rodriguez, Colleen M. Niswender, Weimin Peng, Jerri M. Rook, Sichen Chang, Anna L. Blobaum, Olivier Boutaud, Andrew S. Felts, P. Jeffrey Conn, Craig W. Lindsley, Kayla J. Temple   +21 more
openalex   +1 more source

Metabotropic glutamate receptor type 5 effects on ALS progression

, 2018
Tiziana Bonifacino, Marco Milanese, Marcello Melone, Francesca Provenzano, Aldamaria Puliti, Cesare Usai, Giambattista Bonanno   +6 more
openaire   +1 more source

Biased allosteric modulators at the metabotropic glutamate receptor 5

openaire