Results 261 to 270 of about 478,976 (349)

Biotransformation of a Novel Positive Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Contributes to Seizure-Like Adverse Events in Rats Involving a Receptor Agonism-Dependent Mechanism [PDF]

, 2013
Thomas M. Bridges, Jerri M. Rook, Meredith J. Noetzel, Ryan D. Morrison, Ya Zhou, Rocco D. Gogliotti, Paige N. Vinson, Zixiu Xiang, Carrie K. Jones, Colleen M. Niswender, Craig W. Lindsley, Shaun R. Stauffer, P. Jeffrey Conn, J. Scott Daniels   +13 more
openalex   +1 more source

Inhibiting metabotropic glutamate receptor 5 after stroke restores brain function and connectivity. [PDF]

Brain
Hakon J, Quattromani MJ, Sjölund C, Talhada D, Kim B, Moyanova S, Mastroiacovo F, Di Menna L, Olsson R, Englund E, Nicoletti F, Ruscher K, Bauer AQ, Wieloch T.   +13 more
europepmc   +1 more source

Reduced excitatory amino acid transporter 1 and metabotropic glutamate receptor 5 expression in the cerebellum of fragile X mental retardation gene 1 premutation carriers with fragile X-associated tremor/ataxia syndrome [PDF]

, 2013
Dalyir Pretto, Madhur Kumar, Zhengyu Cao, Christopher L. Cunningham, Blythe Durbin‐Johnson, Lihong Qi, Robert F. Berman, Stephen C. Noctor, Randi J. Hagerman, Isaac N. Pessah, Flora Tassone   +10 more
openalex   +1 more source

μ-Opioid receptor (OPRM1; MOR); metabotropic glutamate receptor subtype 5 (mGluR5; GRM5) [PDF]

, 2013

openalex   +1 more source

The novel peptide LCGM-10 attenuates metabotropic glutamate receptor 5 activity and demonstrates behavioral effects in animal models. [PDF]

Front Behav Neurosci
Malyshev AV, Pavshintcev VV, Mitkin NA, Sukhanova IA, Gedzun VR, Zlobin AS, Doronin II, Babkin GA, Sawyer TK.   +8 more
europepmc   +1 more source

Preliminary Study of White Matter Abnormalities and Associations With the Metabotropic Glutamate Receptor 5 to Distinguish Bipolar and Major Depressive Disorders. [PDF]

Chronic Stress (Thousand Oaks)
Fan S, Asch RH, Davis MT, DellaGioia N, Cool R, Blumberg HP, Esterlis I.   +6 more
europepmc   +1 more source

The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an in vitro model of benign steatosis. [PDF]

Eur J Histochem, 2020
Ferrigno A, Berardo C, Di Pasqua LG, Cagna M, Siciliano V, Richelmi P, Vairetti M.   +6 more
europepmc   +1 more source

Relationship between In Vivo Receptor Occupancy and Efficacy of Metabotropic Glutamate Receptor Subtype 5 Allosteric Modulators with Different In Vitro Binding Profiles [PDF]

, 2014
Jerri M. Rook, Mohammed Noor Tantawy, M. Sib Ansari, Andrew S. Felts, Shaun R. Stauffer, Kyle A. Emmitte, Robert Kessler, Colleen M. Niswender, J. Scott Daniels, Carrie K. Jones, Craig W. Lindsley, P. Jeffrey Conn   +11 more
openalex   +1 more source

Metabotropic glutamate receptor 5 (mGluR5) is associated with neurodegeneration and amyloid deposition in Alzheimer's disease: A [¹⁸F]PSS232 PET/MRI study. [PDF]

Alzheimers Res Ther
Wang J, He Y, Chen X, Huang L, Li J, You Z, Huang Q, Ren S, He K, Schibli R, Mu L, Guan Y, Guo Q, Zhao J, Xie F.   +14 more
europepmc   +1 more source

Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations.

Cell Rep, 2021
Nasrallah C, Cannone G, Briot J, Rottier K, Berizzi AE, Huang CY, Quast RB, Hoh F, Banères JL, Malhaire F, Berto L, Dumazer A, Font-Ingles J, Gómez-Santacana X, Catena J, Kniazeff J, Goudet C, Llebaria A, Pin JP, Vinothkumar KR, Lebon G.   +20 more
europepmc   +1 more source