Results 101 to 110 of about 2,336,805 (315)
JOR SPINE, Volume 8, Issue 3, September 2025.This study explores the role of Central Pattern Generators (CPGs) in locomotor recovery after spinal cord injury (SCI). It examines CPG organization, function, and modulation through amino acids, biogenic amines, and acetylcholine. Therapeutic strategies, including pharmacological, electrical, and optogenetic approaches, are reviewed, alongside current
Hao Su +4 more
wiley +1 more source
Domains involved in the specificity of G protein activation in phospholipase C-coupled metabotropic glutamate receptors. [PDF]
, 1994 Jean‐Philippe Pin +3 more
openalex +1 more source
Central Amygdala Metabotropic Glutamate Receptor 5 in the Modulation of Visceral Pain
Journal of Neuroscience, 2012 Painful bladder syndrome is a debilitating condition that affects 3–6% of women in the United States. Multiple lines of evidence suggest that changes in CNS processing are key to the development of chronic bladder pain conditions but little is known ...
Lara W. Crock +6 more
semanticscholar +1 more source
Recent Developments in the Optical Control of Adrenergic Signaling
Medicinal Research Reviews, Volume 45, Issue 5, Page 1307-1322, September 2025.ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi +4 more
wiley +1 more source
Broad spectrum proteomics analysis of the inferior colliculus following acute hydrogen sulfide exposure. [PDF]
, 2018 Acute exposure to high concentrations of H2S causes severe brain injury and long-term neurological disorders, but the mechanisms involved are not known.
Anantharam, Poojya +8 more
core
Addiction Biology, Volume 30, Issue 9, September 2025.ABSTRACT Chronic nicotine administration leads to neuroadaptations, an important process in nicotine and tobacco dependence for which treatments are limited. The cysteine pro‐drug, N‐acetyl‐cysteine (NAC), is a promising glutamatergic agent that has shown some clinical efficacy in reducing nicotine use in humans.
Kelsey Stoddart +5 more
wiley +1 more source
Metabotropic glutamate receptors mediate excitatory transmission in the nucleus of the solitary tract [PDF]
, 1992 SR Glaum, RJ Miller
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Angewandte Chemie International Edition, Volume 64, Issue 35, August 25, 2025.Controlling protein interactions is key to studying signaling. Antibody methods have limits, but chemical inducers of dimerization (CIDs) using HaloTags and SNAP‐Tags offer precise control. We present CIDs to covalently link heteromers with varied linkers and a FRET‐based sensor.
Michael Trumpp +8 more
wiley +1 more source
Modulation of calcium currents by a metabotropic glutamate receptor involves fast and slow kinetic components in cultured hippocampal neurons [PDF]
, 1993 Yoshinori Sahara, GL Westbrook
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Human Brain Mapping, Volume 46, Issue 12, 15 August 2025.By harmonizing resting‐state fMRI data from a relatively large multi‐site sample, this study reveals altered modular dynamics in schizophrenia. These alterations are associated with multiple neurotransmitter systems and transcriptomic profiles that are preferentially enriched for biological processes of transmembrane transport and brain development, as
Yi Zhen +5 more
wiley +1 more source