Results 171 to 180 of about 2,386,092 (307)

Progress toward therapeutic potential for AFQ056 in Fragile X syndrome

Journal of Experimental Pharmacology, 2013
Mary Sourial, Connie Cheng, Laurie C Doering Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada Abstract: Fragile X syndrome (FXS) is the most common form of inherited intellectual disability and the leading ...
Sourial M, Cheng C, Doering LC
doaj  

Adenosine Receptors in Developing and Adult Mouse Neuromuscular Junctions and Functional Links With Other Metabotropic Receptor Pathways. [PDF]

Front Pharmacol, 2018
Tomàs J, Garcia N, Lanuza MA, Santafé MM, Tomàs M, Nadal L, Hurtado E, Simó-Ollé A, Cilleros-Mañé V, Just-Borràs L.   +9 more
europepmc   +1 more source

Discovery of Novel Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Reveals Chemical and Functional Diversity and In Vivo Activity in Rat Behavioral Models of Anxiolytic and Antipsychotic Activity [PDF]

, 2010
Alice L. Rodriguez, Mark D. Grier, Carrie K. Jones, Elizabeth J. Herman, Alexander S. Kane, Randy L. Smith, Richard D. Williams, Ya Zhou, Joy E. Marlo, Emily Days, Tasha N. Blatt, Satyawan Jadhav, Usha N. Menon, Paige N. Vinson, Jerri M. Rook, Shaun R. Stauffer, Colleen M. Niswender, Craig W. Lindsley, C. David Weaver, P. Jeffrey Conn   +19 more
openalex   +1 more source

Molecular determinants of positive allosteric modulation of the human metabotropic glutamate receptor 2

British Journal of Pharmacology, 2015
A. Farinha, H. Lavreysen, L. Peeters, B. Russo, S. Masure, A. Trabanco, J. Cid, G. Tresadern   +7 more
semanticscholar   +1 more source

Glutamate metabotropic receptor 4 (GRM4) inhibits cell proliferation, migration and invasion in breast cancer and is regulated by miR-328-3p and miR-370-3p. [PDF]

BMC Cancer, 2019
Xiao B, Chen D, Zhou Q, Hang J, Zhang W, Kuang Z, Sun Z, Li L.   +7 more
europepmc   +1 more source

Retrograde modulation of transmitter release by postsynaptic subtype 1 metabotropic glutamate receptors in the rat cerebellum

, 2001
Carole Lévénès, Hervé Daniel, F. Crépel   +2 more
openalex   +1 more source

Evidence for a Fragile X Mental Retardation Protein-Mediated Translational Switch in Metabotropic Glutamate Receptor-Triggered Arc Translation and Long-Term Depression [PDF]

, 2012
Farr Niere, Julia R. Wilkerson, Kimberly M. Huber   +2 more
openalex   +1 more source

Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator

Science, 2014
Huixian Wu, Chong Wang, K. Gregory, K. Gregory, G. Han, Hyekyung P. Cho, Yao Xia, C. Niswender, V. Katritch, J. Meiler, V. Cherezov, P. Conn, R. Stevens   +12 more
semanticscholar   +1 more source

Group III metabotropic glutamate receptors and transient receptor potential vanilloid 1 co-localize and interact on nociceptors [PDF]

, 2012
R. Govea, Siyuan Zhou, Susan M. Carlton
openalex   +1 more source

Exocytosis of Vesicular Zinc Reveals Persistent Depression of Neurotransmitter Release during Metabotropic Glutamate Receptor Long-Term Depression at the Hippocampal CA3–CA1 Synapse [PDF]

, 2006
Jing Qian, Jeffrey L. Noebels
openalex   +1 more source