Regulation of N-methyl-D-aspartate-induced toxicity in the neostriatum: a role for metabotropic glutamate receptors? [PDF]
, 1996 Christopher S. Colwell +3 more
openalex +1 more source
ERNEST COST action overview on the (patho)physiology of GPCRs and orphan GPCRs in the nervous system
British Journal of Pharmacology, Volume 182, Issue 14, Page 3178-3210, July 2025.G protein‐coupled receptors (GPCRs) are a large family of cell surface receptors that play a critical role in nervous system function by transmitting signals between cells and their environment. They are involved in many, if not all, nervous system processes, and their dysfunction has been linked to various neurological disorders representing important
Necla Birgül Iyison +15 more
wiley +1 more source
Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator
Science, 2014 Huixian Wu +12 more
semanticscholar +1 more source
Allosterism in the adenosine A2A and cannabinoid CB2 heteromer
British Journal of Pharmacology, Volume 182, Issue 14, Page 3371-3384, July 2025.Abstract Background and Purpose Allosterism is a regulatory mechanism for GPCRs that can be attained by ligand‐binding or protein–protein interactions with another GPCR. We have studied the influence of the dimer interface on the allosteric properties of the A2A receptor and CB2 receptor heteromer.
Claudia Llinas del Torrent +7 more
wiley +1 more source
Adenosine Receptors in Developing and Adult Mouse Neuromuscular Junctions and Functional Links With Other Metabotropic Receptor Pathways. [PDF]
Front Pharmacol, 2018 Tomàs J +9 more
europepmc +1 more source
Metabotropic glutamate receptor subtypes mediating slow inward tail current (IADP) induction and inhibition of synaptic transmission in olfactory cortical neurones [PDF]
, 1997 Vincenzo Libri +3 more
openalex +1 more source
British Journal of Pharmacology, Volume 182, Issue 14, Page 3225-3248, July 2025.G protein‐coupled receptors (GPCRs) play a crucial role in cell function by transducing signals from the extracellular environment to the inside of the cell. They mediate the effects of various stimuli, including hormones, neurotransmitters, ions, photons, food tastants and odorants, and are renowned drug targets.
Małgorzata M. Kogut‐Günthel +11 more
wiley +1 more source
Metabotropic glutamate receptors modulate [3H]acetylcholine release from cultured amacrine-like neurons [PDF]
, 1999 Olga Caramelo +3 more
openalex +1 more source