Fmr1 deletion enhances and ultimately desensitizes CB1 signaling in autaptic hippocampal neurons
Fragile X Syndrome (FXS) is a heritable form of mental retardation caused by a non-coding trinucleotide expansion of the FMR1 gene leading to loss of expression of this RNA binding protein.
Alex Straiker, Kyung-Tai Min, Ken Mackie
doaj
Sex Differences in Motor Unit Behavior in Patients With Parkinson's Disease
This study utilized high‐density surface electromyography and motor unit decomposition to investigate sex differences in motor unit firing behavior in patients with Parkinson's disease. Females exhibited greater asymmetry in firing properties between more‐ and less‐affected sides, including lower estimates of persistent inward currents (ΔF), higher ...
Yuichi Nishikawa+6 more
wiley +1 more source
Protein Kinase Cbeta and delta Selectively Phosphorylate Odorant and Metabotropic Glutamate Receptors [PDF]
Kathryn F. Medler
openalex +1 more source
LY354740, an agonist of glutamatergic metabotropic receptor mGlu2/3 increases the cytochrome P450 2D (CYP2D) activity in the frontal cortical area of rat brain. [PDF]
Bromek E, Haduch A, Pukło R, Daniel WA.
europepmc +1 more source
Stimulatory effects of the putative metabotropic glutamate receptor antagonist L‐AP3 on phosphoinositide turnover in neonatal rat cerebral cortex [PDF]
Rajendra Mistry+3 more
openalex +1 more source
Estrogenic regulation of hippocampal inhibitory system across lifespan
Abstract Estrogens produced in peripheral tissues and locally in the brain are potent neuromodulators. The function of the hippocampus, a brain region essential for episodic memory and spatial navigation, relies on the activity of ensembles of excitatory neurons whose activity is temporally and spatially coordinated by a wide diversity of inhibitory ...
Pablo Méndez+2 more
wiley +1 more source
Key Grazing Behaviours of Beef Cattle Identify Specific Genotypes of the Glutamate Metabotropic Receptor 5 Gene (GRM5). [PDF]
Moreno García CA+5 more
europepmc +1 more source
Metabotropic NMDA receptor function is required for NMDA receptor-dependent long-term depression
S. Nabavi+5 more
semanticscholar +1 more source
Metabotropic NMDA receptor function is required for β-amyloid–induced synaptic depression
H. Kessels, S. Nabavi, R. Malinow
semanticscholar +1 more source