Altered metabotropic glutamate receptor 5 markers in PTSD: In vivo and postmortem evidence
Proceedings of the National Academy of Sciences of the United States of America, 2017 Sophie E. Holmes +11 more
semanticscholar +1 more source
Metabotropic glutamate receptors trigger postsynaptic protein synthesis.
, 1993 Ivan Jeanne Weiler, William T. Greenough
openalex +1 more source
Electrical stimulation of the prefrontal cortex increases dopamine release in the nucleus accumbens of the rat: modulation by metabotropic glutamate receptors [PDF]
, 1995 M.T Taber, HC Fibiger
openalex +1 more source
Role of Glutamate Excitotoxicity in Glioblastoma Growth and Its Implications in Treatment
Cell Biology International, Volume 49, Issue 5, Page 421-434, May 2025.ABSTRACT Glioblastoma is a highly malignant and invasive type of primary brain tumor that originates from astrocytes. Glutamate, a neurotransmitter in the brain plays a crucial role in excitotoxic cell death. Excessive glutamate triggers a pathological process known as glutamate excitotoxicity, leading to neuronal damage.
Colin Moriarty +2 more
wiley +1 more source
Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1 [PDF]
, 1995 C. Joly +5 more
openalex +1 more source
GABAB Receptor: Structure, Biological Functions, and Therapy for Diseases
MedComm, Volume 6, Issue 5, May 2025.Within the GABAergic system, GABABRs are potential therapeutic targets for dealing multiple metabolic and binge eating disorders and food addiction. Allosteric modulators and small peptides targeting GABABR signaling pathways may be developed as attractive drug candidates that avoid the side effects of agents that directly bind these receptors ...
Weijie Xie +10 more
wiley +1 more source
Axon/Dendrite Targeting of Metabotropic Glutamate Receptors by Their Cytoplasmic Carboxy-Terminal Domains [PDF]
, 1999 Julia Nash Stowell, Ann Marie Craig
openalex +1 more source
MedComm, Volume 6, Issue 5, May 2025.Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes +4 more
wiley +1 more source
Cell Reports, 2019 Summary: Activation of postsynaptic metabotropic glutamate receptors (mGluRs) modulates neuronal excitability and synaptic plasticity, while deregulation of mGluR signaling has been implicated in neurodevelopmental disorders. Overstimulation of mGluRs is
Nicky Scheefhals +5 more
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