Results 131 to 140 of about 37,316 (268)

Oncological Outcomes of Salvage Oropharyngectomy in Irradiated Neck for Recurrent or Metachronous Squamous Cell Carcinoma

open access: yesHead &Neck, Volume 48, Issue 6, Page 1668-1676, June 2026.
ABSTRACT Objective To evaluate oncological outcomes and their predictors following salvage oropharyngectomy. Methods This single‐center retrospective study included patients who underwent a salvage oropharyngectomy in an irradiated neck for recurrent or metachronous oropharyngeal squamous cell carcinoma (OPSCC) between 2014 and 2023.
Jade Saykaly   +8 more
wiley   +1 more source

Risk Factors for Metachronous Gastric Neoplasms in Patients Who Underwent Endoscopic Resection of a Gastric Neoplasm

open access: yesGut and Liver, 2016
Background/Aims : To identify the risk factors for metachronous gastric neoplasms in patients who underwent an endoscopic resection of a gastric neoplasm.
doaj   +1 more source

pH-dependent gating mechanism of the Helicobacter pylori urea channel revealed by cryo-EM. [PDF]

open access: yes, 2019
The urea channel of Helicobacter pylori (HpUreI) is an ideal drug target for preventing gastric cancer but incomplete understanding of its gating mechanism has hampered development of inhibitors for the eradication of H. pylori. Here, we present the cryo-
Cui, Yanxiang   +6 more
core   +1 more source

Spontaneous Middle Cranial Fossa Cerebrospinal Fluid Leaks and Intracranial Hypertension: Systematic Review With Meta‐Analysis

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 3, June 2026.
ABSTRACT Introduction The perioperative management of spontaneous cerebrospinal fluid leaks (sCSFL) of lateral skull base remains under debate. We systematically synthesized and evaluated the current literature, to investigate the perioperative cranial‐pressure assessment protocols and relief methods.
Georgios Vavoulis   +7 more
wiley   +1 more source

Presumed TP53 mosaicism: variants detected using a NGS hereditary cancer multigene panel [PDF]

open access: yes, 2019
Aims/Context: NGS multigene panels are routinely used to identify germline pathogenic variants in cancer susceptibility genes. In addition, NGS allows the identification of low-level mosaicism events that may not be detectable by conventional Sanger ...
Gonçalves, João   +5 more
core  

Impact of the Nadir Androgen Receptor Signaling Inhibitor‐Derived Integrative Response Model in Real‐World Patients With Metastatic Castration‐Sensitive Prostate Cancer

open access: yesThe Prostate, Volume 86, Issue 9, Page 1053-1060, June 15, 2026.
ABSTRACT Background Early deep prostate‐specific antigen (PSA) decline after the initiation of androgen receptor signaling inhibitor (ARSI) therapy is associated with favorable long‐term outcomes in metastatic castration‐sensitive prostate cancer (mCSPC).
Kazuma Yukihiro   +14 more
wiley   +1 more source

Distribution and prognostic value of T‐cells in primary colorectal cancer and adjacent non‐tumor mucosa in stage IV versus stage I–III patients

open access: yesInternational Journal of Cancer, Volume 158, Issue 10, Page 2760-2770, 15 May 2026.
What's New? While colonic mucosa lymphocytes have been quantified in the context of inflammatory diseases, T‐cells in non‐tumor mucosa adjacent to colorectal cancer remain understudied. This study found that in stage IV colorectal cancer (synchronous liver metastasis), higher Foxp3+ T‐cell density and Foxp3+/CD4+ and Foxp3+/CD8+ T‐cell ratios in non ...
Esraa Ali   +10 more
wiley   +1 more source

IMMUNOREACT 9 metachronous rectal cancers have high HLA-ABC expression on healthy epithelium but a lower infiltration of CD3+ T cells than primary lesions

open access: yesScientific Reports
Lynch syndrome is rarely associated with rectal cancer (RC) and thus, metachronous RC has been scarcely investigated. This study aimed to analyze the mucosal immune microenvironment in sporadic and metachronous RC.
Beatrice Salmaso   +72 more
doaj   +1 more source

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