Results 141 to 150 of about 37,316 (268)

Results of the Childhood Cancer and Leukaemia Group's United Kingdom Relapsed Wilms Tumour Trial

Pediatric Blood &Cancer, Volume 73, Issue 5, May 2026.
ABSTRACT Background The United Kingdom relapsed Wilms tumour (UKW‐R) trial aimed to improve the historically low survival rates after relapse of Wilms tumour (WT) through a prospective national risk‐stratified protocol. The trial also evaluated efficacy and toxicity of high‐dose melphalan.
Sucheta J. Vaidya, Veronica Moroz, Juliet Hale, Vesna Pavasovic, Rachel Hobson, Patricia Sartori, Daniel Saunders, Mark Powis, Gordan M. Vujanic, Stephen Baker, Kathy Pritchard‐Jones   +10 more
wiley   +1 more source

Germline Pathogenic Variants in HER2‐Positive Breast Cancer: Spectrum and Clinical Implications in a High‐Risk Chinese Cohort

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Objective Hereditary cancer risk assessment has predominantly focused on HER2‐negative breast cancer (BC), with limited characterization of germline pathogenic variants (GPVs) in HER2‐positive disease. This study aimed to delineate the prevalence, clinicopathological correlates, and clinical implications of GPVs in a cohort of HER2‐positive BC
Lijia Zhou, Mengqian Ni, Anli Yang, Qingru Zhou, Daining Wang, Shu Dun, Fei Xu, Jiajia Huang, Xiwen Bi, Wen Xia, Ruoxi Hong, Qiufan Zheng, Meiting Chen, Kuikui Jiang, Jun Tang, Xi Wang, Zhongyu Yuan, Shusen Wang, Yanxia Shi, Fang Wang, Xin An   +20 more
wiley   +1 more source

TYRO3, AXL, MERTK and Their Ligands in Brain Metastases From Colorectal Cancers

Cancer Medicine, Volume 15, Issue 5, May 2026.
TYRO3, AXL, and MERTK are expressed in primary tumors and extra‐cerebral and brain metastases from colorectal cancers. AXL, primarily expressed in endothelial cells, is the more conserved marker between primary tumor and brain metastasis. The Low AXL/High GAS6 ratio is of poor prognosis in metastatic colorectal cancer patients.
Anaïs Noblanc, Fatima Dkhissi, Pierre‐Olivier Guichet, Lucie Lebeau, Serge Milin, Sheik Emambux, Pauline Roussille, Camille Evrard, Lucie Karayan‐Tapon, David Tougeron, Omar Benzakour, Violaine Randrian   +11 more
wiley   +1 more source

Cytoreductive surgery without intra-peritoneal chemotherapy for metachronous colorectal peritoneal metastases

World Journal of Surgical Oncology
Background Cytoreductive surgery and chemotherapy reportedly improve the prognosis of patients with metachronous peritoneal metastases. However, the types of peritoneal metastases indicated for cytoreductive surgery remains unclear.
Emi Ota, Yosuke Fukunaga, Toshiki Mukai, Yukiharu Hiyoshi, Tomohiro Yamaguchi, Toshiya Nagasaki, Takashi Akiyoshi   +6 more
doaj   +1 more source

Incidence of Second Malignancies Among Children Treated for Cancer With Radiotherapy in Egypt

Cancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Survivors of childhood cancer (CCS) are at risk for secondary malignant neoplasms (SMNs): serious late effects of treatment. Radiotherapy (RT) and chemotherapy (CT) are possible causes of SMNs. Aims To measure SMN incidence and characteristics among Egyptian CCS treated with RT, and to compare SMN timing and location based on RT ...
Charlotte L. Sackett, Mohamed S. Zaghloul, Ahmed Aldesouky, Alaa Elhaddad, Li Zhang, Chloe A. Teasdale, Amr S. Soliman   +6 more
wiley   +1 more source

A Multidisciplinary Approach for a Patient With Synchronous Lip and Thyroid Cancer Involving Radiotherapy

Cancer Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background Synchronous cancers, defined as malignancies diagnosed concurrently or within 2 months of each other, are rare, with an incidence of 1%–6%. Environmental factors such as tobacco smoking play a significant role in their development. Patients with head and neck squamous cell carcinoma (SCC) are at increased risk of second malignancies,
Aleksandra Nasiek, Paweł Polanowski, Marek Hamm, Anna Kozub, Barbara Lipka, Agnieszka Kotecka‐Blicharz, Krzysztof Składowski   +6 more
wiley   +1 more source

Analysis of the structure of deaths from sporadic metachronous primary multiple malignant neoplasms in a general hospital

Бюллетень сибирской медицины
Aim. To analyze the structure of deaths from sporadic metachronous primary multiple malignant neoplasms in 2017–2023 in a multidisciplinary inpatient facility.Materials and methods.
M. V. Zavyalova, A. V. Zavyalov, D. S. Pismenny, L. V. Pikalova, L. D. Zhuykova, Yu. M. Zhuykova, M. Yu. Grishchenko, S. V. Vtorushin, N. V. Litvyakov, M. V. Perelmuter   +9 more
doaj   +1 more source

Diagnostic Utility of Ki‐67 Index on Cell Block Material for Grading Medullary Thyroid Carcinoma

Diagnostic Cytopathology, Volume 54, Issue 5, Page 380-387, May 2026.
ABSTRACT Introduction An international grading system for medullary thyroid carcinoma (IMTCGS) was established in 2022. High‐grade MTC is defined by the presence of one or more of the following features: mitotic index ≥ 5 per 2 mm2, Ki‐67 proliferative index ≥ 5%, or tumor necrosis.
Tieying Hou, Hector Mesa, Bianca Puello, Brent Molden   +3 more
wiley   +1 more source

Value of preoperative magnetic resonance imaging in predicting postoperative recurrence and metastasis of middle rectal cancer

Zhongguo aizheng zazhi, 2018
Background and purpose: Middle rectal cancer has higher local recurrence rate and metachronous distant metastasis rate after radical resection. If the high-risk populations of local recurrence and metachronous distant metastasis can be selected before ...
徐　晔, 周　洋, 唐　娜
doaj  

Bilateral Testicular Tumors Recurred 5 Years After Surgery for an Extragonadal Germ Cell Tumor: Case Report

IJU Case Reports, Volume 9, Issue 3, May 2026.
ABSTRACT Introduction Extragonadal germ cell tumors (EGCT) account for approximately 3%–7% of all germ cell tumors. Metachronous testicular tumors develop in 5%–7% of patients after EGCT treatment; however, bilateral testicular tumors have not been reported. Case Presentation A 30‐year‐old man underwent retroperitoneal tumor resection and was diagnosed
Hiraku Yamamoto, Isao Hara, Satoshi Muraoka, Takahito Wakaymiya, Shimpei Yamashita, Yasuo Kohjimoto   +5 more
wiley   +1 more source