Results 101 to 110 of about 746,734 (318)

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Metadata capture in an electronic notebook: How to make it as simple as possible?

GMS Medizinische Informatik, Biometrie und Epidemiologie, 2015
In the last few years electronic laboratory notebooks (ELNs) have become popular. ELNs offer the great possibility to capture metadata automatically. Due to the high documentation effort metadata documentation is neglected in science.
Menzel, Julia, Weil, Philipp, Nussbeck, Sara Y.   +2 more
doaj   +1 more source

Moving Digital Images [PDF]

, 2014
For over six years the Marquette University Archives managed patron-driven scanning requests using a desktop version of Extensis Portfolio while building thematically-based digital collections online using CONTENTdm.
Sweetser, Michelle
core   +1 more source

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

A Distributed Infrastructure for Metadata about Metadata: The HDMM Architectural Style and PORTAL-DOORS System

Future Internet, 2010
Both the IRIS-DNS System and the PORTAL-DOORS System share a common architectural style for pervasive metadata networks that operate as distributed metadata management systems with hierarchical authorities for entity registering and attribute publishing.
Carl Taswell
doaj   +1 more source

Towards Exascale Scientific Metadata Management

, 2015
Advances in technology and computing hardware are enabling scientists from all areas of science to produce massive amounts of data using large-scale simulations or observational facilities.
Blanas, Spyros, Byna, Surendra
core  

Proposal for an IMLS Collection Registry and Metadata Repository [PDF]

, 2002
The University of Illinois at Urbana-Champaign proposes to design, implement, and research a collection-level registry and item-level metadata repository service that will aggregate information about digital collections and items of digital content ...
Bennett, Nuala A., Cole, Timothy W., Mischo, William H., Palmer, Carole L., Twidale, Michael B.   +4 more
core  

Unveiling Global Diversity of Patescibacteriota and Functional Interactions with Host Microbes

Advanced Science, EarlyView.
Patescibacteriota represents a diverse group of ultra‐small epibiotic bacteria, which is largely overlooked. By integrating ribosomal protein S3‐based community profiling with MAG‐based metabolic potential analyses, this study provides new insights into their distribution, diversity, and potential interactions with other bacteria across diverse ...
Yanhan Ji, Xu Liu, Shuai Zhao, Sihan Zhou, Yufan Yang, Ping Zhang, Yu Shi, Wei Qin, Guibing Zhu, Yongguan Zhu, Yanzheng Gao, Jiandong Jiang, Baozhan Wang   +12 more
wiley   +1 more source

Methods for Standardizing Metadata at Pusdatinrenbang Bappenas

IEEE Access
Metadata interoperability remains a significant challenge for Indonesian government institutions, particularly at Pusdatinrenbang Bappenas, due to the lack of a unified metadata standard.
P. H. Irham Febrieka, Panca Oktavia Hadi Putra   +1 more
doaj   +1 more source

FAIR-EuMon: a FAIR-enabling resource for biodiversity monitoring schemes [PDF]

Biodiversity Data Journal
Within the scope of the Helmholtz Metadata Collaboration (HMC), the ADVANCE project – Advanced metadata standards for biodiversity survey and monitoring data: supporting of research and conservation – aimed at supporting rich metadata generation with ...
Juliana Menger, Barbara Magagna, Klaus Henle, Alexander Harpke, Mark Frenzel, Johannes Rick, Karen Wiltshire, Annegret Grimm-Seyfarth   +7 more
doaj   +3 more sources