Results 101 to 110 of about 22,688 (271)
Advanced Science, EarlyView.Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin +12 more
wiley +1 more source
Advanced Science, EarlyView.SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu +8 more
wiley +1 more source
Balancing between Content Standards and Local Requirements for Scientific Metadata [PDF]
, 2008 This presentation by Jian Qin, School of Information Studies, Syracuse University was hosted by the Metadata Wroking Group of Cornell University Library, 2008-09-19.
Qin, Jian
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BioSharing: harnessing metadata standards for the data commons
, 2017 The use of community-driven metadata standards, such as minimal information guidelines, terminologies, formats/models, is essential to ensure that data and other digital research outputs are Findable, Accessible, Interoperable, and Reusable, according to
Lister, Allyson +13 more
core +1 more source
Advanced Science, EarlyView.This review explores the convergence of artificial intelligence technologies in modeling drug–drug and drug–target interactions. By evaluating advanced feature engineering, architectural innovations, and learning paradigms reveals shared evolutionary trends and critical challenges, such as cold‐start settings and shortcut learning.
Xin Sun, Tong Wang
wiley +1 more source
Advanced Science, EarlyView.Integrated single‐cell mass spectrometry reveals distinct lipidomic signatures that differentiate leader and follower phenotypes in migratory breast cancer cells. Phenotype‐specific alterations across various lipid classes, including fatty acids and phosphatidylcholines, underpin functional heterogeneity.
Xiaoyue Huang +6 more
wiley +1 more source
Metadata queries for complex database systems [PDF]
, 2004 Federated Database Management Systems (FDBS) are very complex. Component databases can be heterogeneous, autonomous and distributed, accounting for these different characteristics in building a FDBS is a difficult engineering problem.
O'Connor, Gerald
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Advanced Science, EarlyView.This perspective proposes a cohesive machine learning strategy to decode microplastic aging. It advocates for Federated Learning to dismantle global data silos and introduces the TRACE framework (TRansport, Aging, Corona, Ecotoxicity). By integrating physics‐informed modeling with causal discovery, this approach bridges the laboratory‐field gap to ...
Yaping Lyu +6 more
wiley +1 more source
Automated Extraction of Multicomponent Alloy Data Using Large Language Models for Sustainable Design
Advanced Science, EarlyView.A large language model (LLM) based pipeline is developed to automatically extract a comprehensive and accurate multicomponent alloy database from literature corpus. The extracted dataset is integrated with sustainability indicators to identify potential alloys that outperform existing industrial benchmark materials in terms of both performance and ...
Aravindan Kamatchi Sundaram +4 more
wiley +1 more source
100 Million Hours of Audiovisual Content: Digital Preservation and Access in the PrestoPRIME Project
, 2010 We report the preliminary results of PrestoPRIME, an EU FP7 integrated project, including audiovisual (AV) archives, academics and industrial partners, focused on long-term digital preservation of AV media objects and on ways to increase access by ...
Boch, Laurent +5 more
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