Results 31 to 40 of about 143,921 (267)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

From anarchy to good practice: the evolution of standards in archaeological computing [PDF]

, 2009
This paper reviews the importance of standards in archaeological computing and traces their development, and the tensions surrounding their deployment. Three categories of standards are defined: technical, content and metadata standards.
Richards, J.D.
core   +3 more sources

Functional requirements for bibliographic description in digital environments

Transinformação
Nowadays in digital information environments, various types of resources coexist with heterogeneous metadata formats and standards and efforts have been made to achieve interoperability in order to use multiple metadata standards and reuse metadata ...
Fabiano Ferreira de Castro
doaj   +1 more source

Designing learning object repositories : a thesis presented in partial fulfilment of the requirements for the degree of Master of Information Science in Information Sciences at Massey University [PDF]

, 2006
Learning object repositories are expanding rapidly into the role of independent educational systems that not only are a supplement to a traditional way of learning, but also allow users to search, exchange and re-use learning objects.
Gan, Yang Yang
core  

Metalexicography as Knowledge Graph [PDF]

, 2019
This short paper presents preliminary considerations regarding LexBib, a corpus, bibliography, and domain ontology of Lexicography and Dictionary Research, which is currently being developed at University of Hildesheim.
Klaes, Christiane, Lindemann, David, Zumstein, Philipp   +2 more
core   +3 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Study of spatial database construction of smart mine

Gong-kuang zidonghua, 2014
The paper discussed construction models of spatial database of smart mine based on analysis of composition and characteristics of mine spatial data, and expounded construction of spatial data framework of smart mine from three aspects which are spatial ...
WANG Li, DU Jiusheng, JING Haitao
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Using Metadata to Build Geographic Information Sharing Environment on Internet [PDF]

Journal of Library and Information Studies, 1999
Internet provides a convenient environment to share geographic information. Web GIS (Geographic Information System) even provides users a direct access environment to geographic databases through Internet. However, the complexity of geographic data makes
Chih-Hong Sun, Shyang-Woei Lin, Han-Wen Shaw   +2 more
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source