Results 31 to 40 of about 7,625,042 (246)

Study of spatial database construction of smart mine

Gong-kuang zidonghua, 2014
The paper discussed construction models of spatial database of smart mine based on analysis of composition and characteristics of mine spatial data, and expounded construction of spatial data framework of smart mine from three aspects which are spatial ...
WANG Li, DU Jiusheng, JING Haitao
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Functional requirements for bibliographic description in digital environments

Transinformação
Nowadays in digital information environments, various types of resources coexist with heterogeneous metadata formats and standards and efforts have been made to achieve interoperability in order to use multiple metadata standards and reuse metadata ...
Fabiano Ferreira de Castro
doaj   +1 more source

Using Metadata to Build Geographic Information Sharing Environment on Internet [PDF]

Journal of Library and Information Studies, 1999
Internet provides a convenient environment to share geographic information. Web GIS (Geographic Information System) even provides users a direct access environment to geographic databases through Internet. However, the complexity of geographic data makes
Chih-hong Sun, Shyang-woei Lin, Han-wen Shaw   +2 more
doaj  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A Descriptive Review of ANSI-NISO Standards with Specific Reference to Their Implications for Digital Library Systems (2015-2023)

Journal of Information Science Theory and Practice
This paper provides a systematic review of American National Standards Institute-National Information Standards Organization (ANSI-NISO) standards that have been published or revised since 2015, and the aim of the paper is to review them in terms of ...
Lili Sahu, Bulu Maharana
doaj   +1 more source

How libraries use publisher metadata

Insights: The UKSG Journal, 2013
With the proliferation of electronic publishing, libraries are increasingly relying on publisher-supplied metadata to meet user needs for discovery in library systems.
Steve Shadle
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Metadata Schema for Managing Digital Data and Images of Thai Human Skulls

Data, 2021
This research was aimed at developing metadata that meets international standards for the purpose of managing digital data and images of Thai human skulls for medical studies.
Satapon Yosakonkun, Panya Tuamsuk, Wirapong Chansanam, Kulthida Tuamsuk   +3 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source