Results 91 to 100 of about 266,079 (291)

LFA: A Lattice Fourier Analyzer for Quantitative In Situ EC‐STM of Adsorbate–Substrate Superstructures

open access: yesAdvanced Materials Interfaces, EarlyView.
Although electrochemical scanning tunneling microscopy provides atomic‐scale access to electrified interfaces, quantitative in situ and operando investigations suffer from drift‐induced distortions. This work introduces the Lattice Fourier Analyzer (LFA), which employs substrate‐anchored affine drift correction in reciprocal space to recover precise ...
Rafał Lewandków   +4 more
wiley   +1 more source

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

open access: yesAdvanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater   +13 more
wiley   +1 more source

Towards Affordable Disclosure of Spoken Word Archives [PDF]

open access: yes, 2008
This paper presents and discusses ongoing work aiming at affordable disclosure of real-world spoken word archives in general, and in particular of a collection of recorded interviews with Dutch survivors of World War II concentration camp Buchenwald ...
Heeren, W.F.L.   +4 more
core   +2 more sources

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

open access: yesAdvanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun   +7 more
wiley   +1 more source

An Experience-Connected e-Learning System with a Personalization Mechanism for Learners’ Situations and Preferences [PDF]

open access: yes, 2011
This paper presents an “experience-connected” e- Learning system that facilitates users to learn practical skills of foreign language by associating knowledge and daily-life experiences.
Nagato , KASAKI   +2 more
core  

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

open access: yesAdvanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance   +17 more
wiley   +1 more source

Evaluating the Alzheimer's disease data landscape

open access: yesAlzheimer’s & Dementia: Translational Research & Clinical Interventions, 2020
Introduction Numerous studies have collected Alzheimer's disease (AD) cohort data sets. To achieve reproducible, robust results in data‐driven approaches, an evaluation of the present data landscape is vital.
Colin Birkenbihl   +8 more
doaj   +1 more source

Hierarchical structuring of Cultural Heritage objects within large aggregations

open access: yes, 2013
Huge amounts of cultural content have been digitised and are available through digital libraries and aggregators like Europeana.eu. However, it is not easy for a user to have an overall picture of what is available nor to find related objects. We propose
C. Gennaro   +6 more
core   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

Top 10 Law School Home Pages of 2011 [PDF]

open access: yes, 2011
For the third consecutive year, the website home pages for all ABA-accredited law schools are evaluated and ranked based on objective criteria. For 2011, law school home pages advanced in some areas.
Skalbeck, Roger
core   +3 more sources

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