Results 41 to 50 of about 8,532,622 (278)
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
GMS Medizinische Informatik, Biometrie und EpidemiologieThis study presents a novel approach to metadata management, while focusing on the development of an automated, microservice-based infrastructure at the University Medical Center Göttingen’s Medical Data Integration Center (UMG-MeDIC). Given the critical
Bönisch, Caroline
doaj +1 more source
A Comparative Study on Metadata Scheme of Chinese and American Open Data Platforms
Zhishi guanli luntan, 2018 [Purpose/significance] Open government data is conducive to the rational development and utilization of data resources. It can encourage social innovation and promote economic development.
Yang Sinan
doaj +1 more source
Critical Metadata Protocols in Hyperspectral Field Campaigns for Building Robust Hyperspectral Datasets [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2012 Field spectroscopic metadata is a central component in the quality and reliability of hyperspectral data and the products derived from it. The impact of the quantity and format of metadata created at this fundamental stage of hyperspectral research is ...
B. Rasaiah +3 more
doaj +1 more source
, 2017 This article analyzes level of metadata quality (MQ ratio) and level of academic visibility in Google Scholar (IGS ratio) associated with coverage of four types of documents (theses, articles, books, and conferences) in repositories of Peruvian ...
Joel Alhuay-Quispe +3 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source