Results 81 to 90 of about 8,532,622 (278)

High‐Throughput Digital Decoding of Vascular Heterogeneity in Patient‐Specific Tumor Microenvironments

Advanced Healthcare Materials, EarlyView.
ABSTRACT Quantitative characterization of vascular heterogeneity in complex microphysiological systems (MPS), particularly within patient‐derived tumor microenvironments, remains a major challenge for scalable disease modeling and therapeutic evaluation.
Jungseub Lee, Wooju Park, Sujin Hyung, Sangmin Jung, Kyungho Lee, Junseok Jeon, Noo Li Jeon, Jeeyun Lee, Hye Ryoun Jang, Jihoon Ko   +9 more
wiley   +1 more source

Evaluating Multilingual Metadata Quality in Crossref

Journal of Librarianship and Scholarly Communication
Introduction: Scholarly research spans multiple languages, making multilingual metadata crucial for organizing and accessing knowledge across linguistic boundaries. These multilingual metadata already exist and are propagated throughout the scholarly publishing infrastructure, but the extent to which they are correctly recorded, or how they affect ...
Dennis Donathan II, Mike Nason, Marco Tullney, Julie Shi, Juan Pablo Alperin   +4 more
openaire   +2 more sources

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

Advanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett, Yann S. Vanrobaeys, Tessy Teboh, Zakiya Smith, Anderson Scott, Cynthia Hajal, Paula T. Hammond, Joelle P. Straehla   +7 more
wiley   +1 more source

Beyond Presumptions: Toward Mechanistic Clarity in Metal‐Free Carbon Catalysts for Electrochemical H2O2 Production via Data Science

Advanced Materials, EarlyView.
Metal‐free carbon catalysts enable the sustainable synthesis of hydrogen peroxide via two‐electron oxygen reduction; however, active site complexity continues to hinder reliable interpretation. This review critiques correlation‐based approaches and highlights the importance of orthogonal experimental designs, standardized catalyst passports ...
Dayu Zhu, Hsi‐wen Wu, Xiao Wang, Jie Zhang   +3 more
wiley   +1 more source

Critical Metadata for Spectroscopy Field Campaigns

Remote Sensing, 2014
A field spectroscopy metadata standard is defined as those data elements that explicitly document the spectroscopy dataset and field protocols, sampling strategies, instrument properties and environmental and logistical variables.
Barbara A. Rasaiah, Simon. D. Jones, Chris Bellman, Tim J. Malthus   +3 more
doaj   +1 more source

Auto‐Routing Fluidic Printed Circuit Boards

Advanced Robotics Research, EarlyView.
This work introduces (STREAM) software tool for routing efficiently advanced macrofluidics, an open‐source software tool for automating the design of 3D‐printable fluidic circuit boards. STREAM streamlines tube routing and layout, enabling the rapid fabrication of fluidic networks for soft robotics, lab‐on‐a‐chip devices, microfluidics, and biohybrid ...
Savita V. Kendre, Lehong Wang, Haotian Liu, Markus P. Nemitz   +3 more
wiley   +1 more source

Quality control of big data analysis for metagenomics

大数据, 2018
Metagenomic data has the characteristics of high volume and complexity.As for data type of metagenomics,it covers metadata and sequencing data.Before performing in-depth functional analysis of metagenomic data,strict quality control for these metadata ...
Guangyong ZHENG, Zhen YANG, Ruifang CAO, Wan LIU, Yixue LI, Guoqing ZHANG   +5 more
doaj  

Curating and sharing XAS data – Metadata and Scientific quality control

Scientific Data
With the growing volume of measured X-ray Absorption Spectroscopy (XAS) data and their need for machine-learning and reference purposes across different facilities, both spectral quality and documentation of the XAS measurements need to be standardized ...
Abhijeet Gaur, Sebastian Paripsa, Frank Förste, Dmitry E. Doronkin, Wolfgang Malzer, Christopher Schlesiger, Birgit Kanngießer, Dirk Lützenkirchen-Hecht, Edmund Welter, Jan-Dierk Grunwaldt   +9 more
doaj   +1 more source

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source